Table 1 Schedule of dose escalation for both RP-G28 and Placebo subjects

Day

Breakfast

Dinner

1–5

-

1.5 g

6–10

-

3.0 g

11–15

-

6.0 g

16–20

1.5 g

6.0 g

21–25

3.0 g

6.0 g

26–30

6.0 g

6.0 g

31–35

7.5 g

7.5 g