Table 1 Demographics Counts (%) are reported unless otherwise noted
| Â | Patients | Controls and family groups | ||||
|---|---|---|---|---|---|---|
Crohn’s disease (n = 34) | Ulcerative colitis (n = 21) | Patients’ family (n = 55) | Healthy control (n = 48) | Controls’ family (n = 48) | ||
Age, mean ± SD | 39.9 ± 12.3 yr | 44.2 ± 13.7 yr | 46.5 ± 21.6 yr | 39.6 ± 13.8 yr | 30.5 ± 18.7 yr | |
Sex: female | 21 (61.8%) | 13 (61.9%) | 42 (76.4%) | 38 (79.2%) | 30 (62.5%) | |
BMI, mean ± SD | 24.2 ± 4.1 kg/m2 | 25.4 ± 3.2 kg/m2 | 24.6 ± 4.6 kg/m2 | 25.7 ± 7.9 kg/m2 | 24.9 ± 6.5 kg/m2 | |
Ethnicity: | Caucasian* | 32 (94.1%) | 20 (95.2%) | 51 (92.7%) | 38 (79.2%) | 38 (79.2%) |
Jewish | 15 (44.1%) | 13 (61.9%) | 29 (52.7%) | 20 (41.6%) | 20 (41.6%) | |
Seasons: | Sunny: May - Sept | 15 (44.1%) | 10 (47.6%) | 28 (50.9%) | 21 (43.8%) | 22 (45.8%) |
Less Sunny: Oct. - Apr | 19 (55.9%) | 11 (52.3%) | 27 (49.1%) | 27 (56.3%) | 26 (54.2%) | |
Smoking^ | 3 (8.8%) | 3 (14.3) | 5 (9.1%)^ | 6 (12.5)% | 2 (4.2)% | |
Regular tanning^ | 0 | 1 (4.8%) | 0 | 1 (2.1)% | 1 (2.1)% | |
Vacation 1Â month pretest^ | 4 (11.8%) | 0 | 3 (5.5)% | 4 (8.3%) | 1 (2.1)% | |
Activity score**, mean ± SD | 2.6 ± 1.9 (20.6% mild active) | 2 ± 1.3 (0% active) |  |  |  | |
Disease Duration, mean ± SD | 85.6 ± 140.2 month | 39.7 ± 53.5 month |  |  |  | |
Site of disease | Colon | 13 (38.2%) | Pan Colitis: 16 (76.2%) | Â | Â | Â |
Ileo-colon | 12 (35.3%) | Left limit: 4 (19%) | Â | Â | Â | |
Small bowel | 9 (26.6%) | Unclear: 1 (5%) | Â | Â | Â | |
Medical: | 5ASA | 6 (17.7%) | 17 (81%) | Â | 0 | 1 diagnosed with leukemia |
Corticosteroids | 4 (11.8%) | 4 (19%) | ||||
Immunomodulators | 5 (14.7%) | N1 (4.8%) | ||||
Biologics | 3 (8.8%) | 3 (14.3%) | ||||
Surgical history: | Colon | 0 | Colectomy: 1 (4.8%) | Â | Â | Â |
Colon and/or Small Bowel | 11 (32.4%) | Â | Â | Â | Â | |
Ileostomy | 3 (8.8%) | Â | Â | Â | Â | |