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Table 4 Adverse events after intervention.

From: Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial

Characteristics

Vitamin C Group

(n = 70)

Placebo

Group (n = 71)

Withdrawal from trial for adverse events, n (%)

0 (0)

0 (0)

Patients with ≥ 1 adverse events 2 hours after trial, n (%)

16 (22.9)

11 (15.4)

Patients with ≥ 1 adverse events 1 day after trial, n (%)

4 (5.7)

4 (5.6)

Total adverse events, n

24

17

Patients who experienced specific adverse events 2 hours after intervention, n (%)

 

itching sense/pain at injection site

9 (12.9)

8 (11.3)

dry mouth

7 (10)

2 (2.8)

others*

4 (5.7)

3 (4.2)

Patients who experienced specific adverse events 1 day after intervention, n (%)

 

itching sense/pain at injection site

1 (1.4)

3 (4.2)

dry mouth

1 (1.4)

0 (0)

diarrhea

1 (1.4)

0 (0)

common cold symptoms

1 (1.4)

1 (1.4)

  1. *Other adverse events included chest discomfort, palpitations, sweating, and abdominal discomfort in the vitamin C group and dizziness, fatigue, and myalgias in the placebo group. These adverse events occurred in one case each.