Skip to main content

Table 4 Adverse events after intervention.

From: Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial

Characteristics Vitamin C Group
(n = 70)
Placebo
Group (n = 71)
Withdrawal from trial for adverse events, n (%) 0 (0) 0 (0)
Patients with ≥ 1 adverse events 2 hours after trial, n (%) 16 (22.9) 11 (15.4)
Patients with ≥ 1 adverse events 1 day after trial, n (%) 4 (5.7) 4 (5.6)
Total adverse events, n 24 17
Patients who experienced specific adverse events 2 hours after intervention, n (%)  
itching sense/pain at injection site 9 (12.9) 8 (11.3)
dry mouth 7 (10) 2 (2.8)
others* 4 (5.7) 3 (4.2)
Patients who experienced specific adverse events 1 day after intervention, n (%)  
itching sense/pain at injection site 1 (1.4) 3 (4.2)
dry mouth 1 (1.4) 0 (0)
diarrhea 1 (1.4) 0 (0)
common cold symptoms 1 (1.4) 1 (1.4)
  1. *Other adverse events included chest discomfort, palpitations, sweating, and abdominal discomfort in the vitamin C group and dizziness, fatigue, and myalgias in the placebo group. These adverse events occurred in one case each.