Table 1 Effects of Rimonabant with dietary intervention on physical and biochemical parameters over the study period (n = 20) (Mean ± SD)
Baseline | 6 Months | |
|---|---|---|
Weight (Kg) | 112 ± 21 | 107 ± 21*** |
Waist circumference (cm) | 124 ± 13 | 121 ± 13** |
Fat mass (Kg) | 44 ± 12 | 42 ± 12 |
HbA1c (%) | 8.0 ± 1.6 | 7.4 ± 1.7* |
Total cholesterol (mmol/L) | 4.4 ± 1.0 | 4.4 ± 1.0 |
LDL cholesterol (mmol/L) | 2.3 ± 0.8 | 2.4 ± 0.9 |
HDL cholesterol (mmol/L) | 1.2 ± 0.2 | 1.3 ± 0.2** |
Triglyceride (mmol/L) | 1.9 ± 1.1 | 1.7 ± 0.9 |
Insulin dose (units / day) | 116 ± 59 | 102 ± 71* |
Systolic blood pressure (mmHg) | 147 ± 21 | 142 ± 24 |
Diastolic blood pressure (mmHg) | 85 ± 8 | 83 ± 11 |