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Table 3 Faecal bacterial numbers (log 10 cells/g faeces) determined by fluorescent in situ hybridisation for forty volunteers over the trial period during which they were consuming “placebo” or “AXOS” experimental bread products enriched with AXOS (mean values and standard deviations)

From: A randomised, double-blind, placebo controlled cross-over study to determine the gastrointestinal effects of consumption of arabinoxylan-oligosaccharides enriched bread in healthy volunteers

  baseline control bread pre- placebo treatment placebo treatment post- placebo washout pre- AXOS treatment AXOS treatment post- AXOS washout
Bifidobacterium 9.14 ±0.57 9.37 ±0.59 a 9.32 ±0.58 a 9.31 ±0.44 a 9.33 ±0.33 a 9.39 ±0.40 a 9.40 ±0.42 a 9.34 ±0.40 a
Clostridium histolyticum group 8.35 ±0.72 8.43 ±0.69   8.07 ±0.64   8.04 ±0.76 a 8.05 ±0.85 a 8.14 ±0.79   8.13 ±0.74   8.14 ±0.57  
E. coli 7.20 ±0.39 7.35 ±0.56   7.38 ±0.47 a 7.33 ±0.40   7.34 ±0.45   7.34 ±0.53   7.34 ±0.50 a 7.40 ±0.39 a
Lactobacillus – Enterococcus 8.85 ±0.54 8.92 ±0.37   8.60 ±0.66   8.95 ±0.55 b 8.72 ±0.75   8.74 ±0.69   9.05 ±0.40 bc 8.69 ±0.71  
Atopobium Coriobacterium group 9.73 ±0.24 9.80 ±0.27   9.79 ±0.28   9.84 ±0.34   9.87 ±0.26 a 9.88 ±0.28 a 9.79 ±0.21   9.87 ±0.26 a
E. rectale group 9.96 ±0.27 9.87 ±0.33   9.91 ±0.33 c 10.07 ±0.29 ab 10.08 ±0.29 a b 9.99 ±0.33   10.01 ±0.34   10.08 ±0.32 a
Total bacteria 10.73 ±0.22 10.69 ±0.22   10.70 ±0.25   10.72 ±0.20   10.68 ±0.22   10.72 ±0.18   10.81 ±0.21 b 10.72 ±0.25  
Bacteroides 9.54 ±0.32 9.64 ±0.44   9.85 ±0.46 ac 10.07 ±0.25 ab 10.11 ±0.29 a b 9.91 ±0.42 ac 9.99 ±0.34 abc 10.12 ±0.22 a b
Roseburia – Eubacteria 9.65 ±0.21 9.69 ±0.26   9.57 ±0.44   9.79 ±0.39 ab 9.67 ±0.51   9.74 ±0.27   9.73 ±0.32   9.61 ±0.47  
Faecalibacterium prausnitzii cluster 9.57 ±0.42 9.48 ±0.44   9.53 ±0.40   9.65 ±0.33 b 9.52 ±0.46   9.50 ±0.51 c 9.56 ±0.38   9.67 ±0.41 b
  1. A paired t-test was used to compare bacteria levels at different time points, for E. coli the non parametric Wilcoxon signed rank test was used, as this data did not follow a normal distribution.
  2. a - different to baseline; b- different to pre-treatment; c- different to washout, (p < 0.05).