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Table 1 Clinical and biochemical characteristics of CHC virus infection patients according genotype classification

From: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil

  GENOTYPE 1
(N = 93)
GENOTYPE NON-1
(N = 45)
P
Age 54.06 51.59 0.14
Fasting Glucose 92.58 100.13 0.80
Homocysteine* (μmol/L) 9.96 9.39 0.01*
HOMA 2.72 3.35 0.74
AST (UI) 68.69 73.24 0.97
ALT(UI) 84.02 91.56 0.58
γGT(UI) 86.06 84.31 0.93
AP(UI) 83.03 72.67 0.26
Total Cholesterol*(mg/dL) 158.01 138.58 0.01*
HDL (mg/dL) 49.05 46.73 0.29
LDL(mg/dL) 88.00 74.44 0.10
Triglycerides (mg/dL) 105.89 91.69 0.05*
  1. *p significative
  2. References values:
  3. AST: Male- 10-34 UI, Female- 10-36 UI; ALT: Male- 10-44 UI, Female-10-36 UI;
  4. γGT: Male- 11-50 UI, Female-7-32 UI; AP: Male- 45-122 UI, Female-32-104 UI; Cholesterol: < 200
  5. mg/dl; Triglycerides: < 150 mg/dl; HDL: > 40 mg/dl; Glucose: < 100 mg/dl; HOMA homeostasis
  6. model assessment for insulin resistence (value < 2.5), Homocysteine < 9.0 μmol/L.