From: The role of soluble fiber intake in patients under highly effective lipid-lowering therapy
RSV+Fib | RSV | SIM/EZE+Fib | SIM+EZE | P-value1 | P-value2 | |
---|---|---|---|---|---|---|
N = 28 | N = 30 | N = 28 | n = 30 | |||
Weight kg | ||||||
Baseline | 74 (3) | 72 (2) | 73 (3) | 70 (2) | 0.001 | 0.803 |
12 weeks | 73 (3) | 72 (3) | 72 (3) | 70 (2) | ||
BMI kg/m2 | ||||||
Baseline | 28 (1) | 30 (1) | 30 (1) | 28 (1) | 0.005 | 0.246 |
12 weeks | 27 (1) | 30 (1) | 29 (1) | 28 (1) | ||
Glucose mg/dL | ||||||
Baseline | 97 (2) | 104 (4) | 103 (5) | 108 (7) | 0.754 | 0.257 |
12 weeks | 95 (2) | 104 (4) | 100 (4) | 109 (6) | ||
HbA1c % | ||||||
Baseline | 5.7 (0.1) | 6.3 (0.2) | 6.0 (0.2) | 6.2 (0.2) | 0.02 | 0.215 |
12 weeks | 5.8 (0.1) | 6.2 (0.2) | 6.1 (0.2) | 6.3 (0.2) | ||
hsCRP mg/L | ||||||
Baseline | 4.2 (1.1) | 3.7 (0.5) | 3.3 (0.4) | 4.5 (1.3) | <0.001 | 0.976 |
12 weeks | 2.4 (0.5) | 2.5 (0.4) | 2.3 (0.4) | 2.3 (0.4) | ||
Cholesterol mg/dL | ||||||
Baseline | 256 (10) | 244 (8) | 247 (8) | 241 (9) | <0.0001 | 0.639 |
12 weeks | 149 (6) | 140 (5) | 155 (9) | 147 (8) | ||
LDL-C mg/dL | ||||||
Baseline | 167 (8) | 154 (7) | 162 (6) | 158 (8) | <0.001 | 0.436 |
12 weeks | 70 (5) | 64 (4) | 80 (8) | 72 (4) | ||
HDL-C mg/dL | ||||||
Baseline | 57 (3) | 52 (2) | 52 (2) | 54 (2) | 0.392 | 0.351 |
12 weeks | 57 (3) | 50 (3) | 53 (3) | 52 (2) | ||
Triglycerides mg/dL | ||||||
Baseline | 160 (13) | 187 (16) | 158 (14) | 144 (10) | <0.001 | 0.291 |
12 weeks | 110 (9) | 123 (8) | 110 (7) | 108 (9) | ||
Apoliprotein A1 mg/dL | ||||||
Baseline | 153 (6) | 145 (6) | 141 (4) | 147 (3) | 0.035 | 0.482 |
12 weeks | 155 (6) | 149 (6) | 145 (5) | 152 (4) | ||
Apoliprotein B mg/dL | ||||||
Baseline | 133 (6) | 133 (5) | 133 (5) | 134 (6) | <0.001 | 0.775 |
12 weeks | 68 (3) | 67 (3) | 73 (5) | 70 (4) | ||
Campesterol mg/dL | ||||||
Baseline | 1.2 (0.2) | 1.1 (0.1) | 0.9 (0.1) | 1.3 (0.2) | <0.001 | 0.005 |
12 weeks | 0.9 (0.1) | 1.0 (0.1) | 0.5 (0.1) | 0.8 (0.1) | ||
β-sitosterol mg/dL | ||||||
Baseline | 0.7 (0.1) | 0.8 (0.1) | 0.6 (0.1) | 0.9 (0.1) | 0.03 | 0.072 |
12 weeks | 0.6 (0.6) | 0.7 (0.1) | 0.5 (0.1) | 0.6 (0.1) | ||
Desmosterol mg/dL | ||||||
Baseline | 0.7 (0.1) | 1.9 (1.6) | 0.9 (0.3) | 0.5 (0.1) | 0.005 | 0.373 |
12 weeks | 0.6 (0.1) | 0.9 (0.5) | 1.0 (0.3) | 1.6 (0.5) |