Longitudinal study of leptin levels in chronic hemodialysis patients

Nutrition Journal

Table 1 Unadjusted and multivariate adjusted Spearman's correlation coefficients of baseline serum leptin and nutritional clinical and laboratory parameters in the study population at baseline

	Raw		Adjusted^a
	R	P	R	P
Dietary intake
Energy intake (kcal/kg/d)	-0.133	0.21	-0.170	0.17
Protein intake (g/kg/d)	-0.231	0.027	-0.177	0.15
nPNA	0.005	0.97	0.079	0.46
Biochemical markers
Albumin (g/dL)	0.216	0.030	0.065	0.55
Creatinine (mg/dL)	-0.014	0.89	0.082	0.44
Cholesterol (mg/dL)	0.217	0.029	0.060	0.57
Transferrin (mg/dL)	0.161	0.11	0.056	0.61
IL-6 (mcg/ml)	-0.105	0.31	0.012	0.92
Anthropometric measurements
BMI (kg/m ² )	0.758	< 0.001	-	-
TSF (mm)	0.696	< 0.001	0.319	0.008
MAC (cm)	0.751	< 0.001	0.491	< 0.001
MAMC (cm)	0.486	< 0.001	0.378	0.001
Bioimpedance analysis
FMI (kg/m ² )	0.862	< 0.001	-	-
FFMI (kg/m ² )	0.247	0.013	0.296	0.014
Phase angle (°)	0.273	0.006	0.128	0.297

Correlation coefficient values ≥ 0.25 appear in bold.
^a All case-mix-adjusted models include age, gender, DM status, dialysis vintage, CV disease in the past and fat mass.
Abbreviations: nPNA, normalized protein nitrogen appearance; IL-6, interleukin-6; BMI, body mass index; TSF, triceps skinfold thickness; MAC, mid-arm circumference; MAMC, mid-arm muscle circumference calculated; FMI, fat mass index; FFMI, fat-free mass index, DM, diabetes mellitus; CV, cardio-vascular.

ISSN: 1475-2891