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Table 5 Treatment acceptance and adherence

From: Efficacy of different strategies to treat anemia in children: a randomized clinical trial

Outcome variables

IS

IFS

MMS

FW

FCF

P

Acceptance of the treatment:

      

   Trouble taking the treatment

3.7 (3.1, 4.2) 2

1.9 (1.5, 2.4) 3

6.4 (5.5, 7.2) 1

1.3 (1.0, 1.6) 4

2.3 (1.9, 2.8) 3

< 0.001

   Child dislike of the treatment

5.1 (4.4, 5.8) 2

3.1 (2.6, 3.7) 3

7.4 (6.5, 8.4) 1

2.0 (1.6, 2.3) 4

3.1 (2.6, 3.6) 3

< 0.001

Adherence to the treatment:

      

   Completed 80% of treatment dose, %

91.5 (83.4, 99.7)

89.2 (79.1, 99.4)

84.6 (71.9, 97.2)

*

89.1 (80.1, 98.0)

0.795

   Completed 4 m of treatment, %

83.2 (72.8, 93.6)

84.9 (74.5, 95.2)

71.0 (57.7, 84.4)

86.3 (77.1, 95.5)

88.5 (80.0, 97.0)

0.168

  1. Treatment abbreviations: Iron supplement (IS), iron plus folic acid supplement (IFS), multiple micronutrients supplement (MMS), micronutrient fortified complementary food as porridge powder (FCF), or zinc, iron and ascorbic acid fortified water (FW)
  2. Values are estimated means (95%C.I.) adjusted for age and baseline Hb. P value for the treatment main effect evaluated in a generalized linear model assuming the poisson distribution and log link function for adherence and rejection to the treatment variables and the binomial distribution and logit link function for the completion of the study variable. Models were adjusted for community, baseline Hb, age and gender.
  3. * FW treatment does not have an adherence reference parameter, thus this treatment was not included in the model.
  4. † Number of weekly visits that the mother reported difficulty to give the treatment to the child
  5. 1-4Different numbers indicate significant difference in the Least Significant Test at p < 0.05.