Concentrated oat β-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial

Table 3 Total SCFA^†, acetate, propionate, and butyrate production^‡ (μmol/ml) of isolated oat β-glucan (54% soluble fiber), guar gum sample (MW 400 kDa) and inulin sample (degree of polymerization 100% ≈10) after 0, 4,8,12, and 24 hours in a model intestinal fermentation, analyzed by gas chromatography.

Sample		Oat β-glucan	Guar Gum	Inulin
Total SCFA	0 h	0.6 ± 0.2	-0.7 ± 0.5	-0.3 ± 0.2
	4 h	32.7 ± 0.3^a*	7.7 ± 0.02^b	33.8 ± 0.8^a
	8 h	50.5 ± 4.0^a	45.7 ± 3.2^a	75.4 ± 0.7^b
	12 h	50.3 ± 6.2	62.0 ± 0.6	55.6 ± 1.8
	24 h	48.7 ± 1.5^a	68.6 ± 0.8^b	51.8 ± 0.8^a
Acetate	0 h	-0.4 ± 0.01	-0.2 ± 0.05	-0.2 ± 0.02
	4 h	23.1 ± 0.9^a	6.6 ± 0.5^b	23.3 ± 0.4^a
	8 h	40.0 ± 3.1^a	34.2 ± 2.2^a	63.7 ± 1.8^b
	12 h	37.5 ± 4.5	45.5 ± 0.1	48.2 ± 4.2
	24 h	24.7 ± 1.7^a	34.6 ± 0.2^b	30.3 ± 0.8^ab
Propionate	0 h	-0.1 ± 0.01	0.05 ± 0.04	-0.04 ± 0.01
	4 h	0.7 ± 0.04	0.5 ± 0.1	0.4 ± 0.1
	8 h	0.8 ± 0.7^a	4.5 ± 0.8^b	-2.2 ± 0.1^a
	12 h	3.8 ± 1.2^a	16.8 ± 0.3^b	-6.2 ± 0.2^c
	24 h	11.9 ± 0.004^a	28.5 ± 0.7^b	0.08 ± 0.1^c
Butyrate	0 h	-0.1 ± 0.02	-0.03 ± 0.04	-0.03 ± 0.02
	4 h	0.4 ± 0.02	0.2 ± 0.05	0.2 ± 0.04
	8 h	2.2 ± 0.3^a	0.9 ± 0.2^b	0.6 ± 0.05^b
	12 h	7.7 ± 0.9^a	3.3 ± 0.1^b	-.004 ± 0.1^c
	24 h	13.3 ± 0.3^a	6.8 ± 0.1^b	23.1 ± 0.1^c

^† Total SCFA = acetate, propionate, butyrate, isobutyrate, 2-methylbutyrate, isovalerate, lactate, and valerate (if detectable).
^‡Values shown are mean ± standard error, each from 2 samples
*Mean production of each compound was compared at each time point between oat β-glucan, guar gum, and inulin. Within each row, means that do not share a superscript letter are significantly different (p < 0.05), and means that share a letter are not significantly different.

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