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Table 3 Effect of diet-induced H + load on factors for both creatinine and uric acid clearances

From: Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid

 

alkaline diet

acidic diet

p

 

(n = 19)

(n = 19)

 

serum uric acid (mg/dL)

4.3 ± 0.8

4.9 ± 0.6

<0.01

serum creatinine (mg/dL)

0.58 ± 0.08

0.63 ± 0.06

NS

urine uric acid (mg/dL)

37.0 ± 11.2

25.9 ± 10.0

<0.01

urine creatinine (mg/dL)

78.9 ± 24.3

79.3 ± 18.0

NS

urine volume (mL/day)

1270 ± 436

1429 ± 320

NS

Uric acid clearance (mL/min/1.73 m2)

8.6 ± 2.3

6.0 ± 2.2

<0.01

Creatinine clearance (mL/min/1.73 m2)

133.9 ± 19.7

138.8 ± 21.4

NS

  1. All numerical data were collected from records during the 3rd and 5th experimental days.