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Table 4 Genotype frequencies of the 677C/T (MTHFR) polymorphisms in CHC patients according genotype and histopathological classification

From: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil

 

Genotype frequencies (%)

MTHFR

TT

CT

CC

p

Steatosis (n = 104)

5.7

40.4

53.8

0.80

No Steatosis (n = 70)

7.1

41.4

51.4

 

Fibrosis 1+2 (n = 116)

5.1

37.9

56.9

0.21

Fibrosis 3+4 (n = 58)

8.6

46.5

44.8

 

Genotype 1 (n = 113)

4.4

35.4

60.1

0.01*

Genotype Non-1 (n = 61)

9.8

50.8

39.3

 
  1. *p significative