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Table 1 Clinical and biochemical characteristics of CHC virus infection patients according genotype classification

From: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil

 

GENOTYPE 1

(N = 93)

GENOTYPE NON-1

(N = 45)

P

Age

54.06

51.59

0.14

Fasting Glucose

92.58

100.13

0.80

Homocysteine* (ÎĽmol/L)

9.96

9.39

0.01*

HOMA

2.72

3.35

0.74

AST (UI)

68.69

73.24

0.97

ALT(UI)

84.02

91.56

0.58

ÎłGT(UI)

86.06

84.31

0.93

AP(UI)

83.03

72.67

0.26

Total Cholesterol*(mg/dL)

158.01

138.58

0.01*

HDL (mg/dL)

49.05

46.73

0.29

LDL(mg/dL)

88.00

74.44

0.10

Triglycerides (mg/dL)

105.89

91.69

0.05*

  1. *p significative
  2. References values:
  3. AST: Male- 10-34 UI, Female- 10-36 UI; ALT: Male- 10-44 UI, Female-10-36 UI;
  4. ÎłGT: Male- 11-50 UI, Female-7-32 UI; AP: Male- 45-122 UI, Female-32-104 UI; Cholesterol: < 200
  5. mg/dl; Triglycerides: < 150 mg/dl; HDL: > 40 mg/dl; Glucose: < 100 mg/dl; HOMA homeostasis
  6. model assessment for insulin resistence (value < 2.5), Homocysteine < 9.0 ÎĽmol/L.