Index score segments | ||||||
---|---|---|---|---|---|---|
Characteristica | All | 1 | 2 | 3 | 4 | 5 |
BSDS scores | 12.9 ± 4.1 | 0–8 | 9–11 | 12–13 | 14–16 | 17–24 |
Observations, n | 969 | 131 | 240 | 170 | 226 | 202 |
Age, years | 54 ± 7.4 | 52 ± 8.5 | 52 ± 8.4 | 54 ± 7.2 | 55 ± 6.2 | 56 ± 6.0 |
Sex (% female) | 46 | 49 | 44 | 48 | 43 | 49 |
School education (%) | ||||||
Base level | 66 | 74 | 68 | 60 | 67 | 62 |
High school | 15 | 17 | 21 | 14 | 12 | 12 |
University | 19 | 9 | 12 | 26 | 21 | 27 |
BMI, kg/m2 | 26.0 ± 3.7 | 25.6 ± 3.9 | 26.0 ± 4.0 | 25.9 ± 3.6 | 26.2 ± 3.3 | 26.4 ± 4.0 |
Physical activity (%) | ||||||
Low | 77 | 88 | 82 | 79 | 75 | 63 |
Medium | 20 | 11 | 16 | 17 | 22 | 31 |
High | 4 | 2 | 3 | 5 | 4 | 6 |
Smoking (%) | 18 | 14 | 17 | 19 | 23 | 16 |
Metabolites (µmol/L) | ||||||
Choline | 8.9 ± 1.6 | 8.6 ± 1.6 | 8.9 ± 1.7 | 8.8 ± 1.5 | 8.9 ± 1.6 | 9.2 ± 1.7 |
Betaine | 31.0 ± 7.2 | 29.6 ± 6.4 | 31.3 ± 7.2 | 30.2 ± 7.0 | 31.1 ± 7.5 | 33.1 ± 14.9 |
tHcy | 10.5 ± 4.7 | 10.6 ± 3.3 | 11.3 ± 6.0 | 10.3 ± 4.2 | 10.7 ± 5.7 | 9.6 ± 2.3 |
DMG | 3.8 ± 1.8 | 3.8 ± 2.0 | 3.9 ± 1.8 | 3.8 ± 2.2 | 3.7 ± 1.5 | 3.8 ± 1.5 |
Sarcosine | 1.9 ± 1.1 | 1.8 ± 1.0 | 1.9 ± 1.1 | 1.9 ± 1.2 | 1.9 ± 1.2 | 1.9 ± 1.1 |
Glycine | 244 ± 73 | 235 ± 60 | 241 ± 69 | 253 ± 76 | 243 ± 77 | 247 ± 77 |
Serine | 110 ± 19 | 108 ± 17 | 111 ± 20 | 111 ± 19 | 110 ± 19 | 111 ± 20 |