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Table 1 Baseline characteristics of the study population

From: Efficacy of Global Leadership Initiative on Malnutrition as potential cachexia screening tool for patients with solid cancer

 

All cancer

Non-cachexia

Cachexia

 

Characteristics

(n = 8478)

(n = 7037)

(n = 1441)

P

Age, y, mean (SD)

56.75 (12.05)

56.54 (11.83)

57.77 (13.01)

< 0.001

 < 65

6218 (73.30)

5217 (74.10)

1001 (69.50)

< 0.001

 ≥ 65

2260 (26.70)

1820 (25.90)

440 (30.50)

 

Sex, n (%)

 Male

4338 (51.20)

3465 (49.20)

873 (60.60)

< 0.001

 Female

4140 (48.80)

3572 (50.80)

568 (39.40)

 

BMI, kg/m2, mean (SD)

22.88 (3.47)

23.57 (3.06)

19.53 (3.39)

< 0.001

TNM, n (%)

 I

1261 (14.90)

1137 (16.20)

124 (8.60)

< 0.001

 II

2052 (24.20)

1779 (25.30)

273 (18.90)

 

 III

2938 (34.70)

2388 (33.90)

550 (38.20)

 

 IV

2227 (26.30)

1733 (24.60)

494 (34.30)

 

Smoke, yes, n (%)

3357 (39.60)

2675 (38.00)

682 (47.30)

< 0.001

Complication, yes, n (%)

2727 (32.2)

2266 (32.2)

461 (32.0)

0.901

Alcohol, yes, n (%)

1569 (18.50)

1222 (17.40)

347 (24.10)

< 0.001

Anorexia, yes, n (%)

1092 (12.90)

734 (10.40)

358 (24.80)

< 0.001

NRS-2002, ≥ 3, n (%)

2217 (26.20)

938 (13.30)

1279 (88.80)

< 0.001

PGSGA, n (%)

 0–3

4304 (50.80)

4105 (58.30)

199 (13.80)

< 0.001

 4–8

2594 (30.60)

2093 (29.70)

501 (34.80)

 

 ≥ 9

1580 (18.60)

839 (11.90)

741 (51.40)

 

GLIM-step1, n (%)

 Well nourished

4271 (50.40)

4271 (60.70)

0 (0.00)

< 0.001

 Moderate malnutrition

2800 (33.00)

1992 (28.30)

808 (56.10)

 

 Severe malnutrition

1407 (16.60)

774 (11.00)

633 (43.90)

 

GLIM-step2, n (%)

 Well nourished

6624 (78.10)

6462 (91.80)

162 (11.20)

< 0.001

 Moderate malnutrition

1122 (13.20)

425 (6.00)

697 (48.40)

 

 Severe malnutrition

732 (8.60)

150 (2.10)

582 (40.40)

 

KPS, Mean (SD)

87.09 (12.79)

88.12 (11.69)

82.04 (16.28)

< 0.001

Albumin (g/L), Mean (SD)

39.53 (10.49)

39.89 (8.52)

37.78 (17.01)

< 0.001

 ≥ 35

6883 (81.20)

5924 (84.20)

959 (66.60)

< 0.001

 < 35

1595 (18.80)

1113 (15.80)

482 (33.40)

 

NLR, Mean (SD)

3.70 (7.15)

3.5 (6.64)

4.69 (9.19)

< 0.001

MAC (cm), Mean (SD)

26.58 (3.55)

27.08 (3.31)

24.16 (3.69)

< 0.001

TSF (mm), Mean (SD)

16.90 (8.01)

17.79 (7.89)

12.59 (7.19)

< 0.001

MAMC (cm), Mean (SD)

20.83 (3.43)

21.03 (3.42)

19.88 (3.27)

< 0.001

CC (cm), Mean (SD)

33.23 (3.91)

33.72 (3.68)

30.80 (4.07)

< 0.001

  1. All of other cancer were solid neoplasms, including bladder cancer, prostate cancer, endometrial cancer, brain malignant tumor, gastric stromal tumor and biliary tract cancer
  2. SD Standard deviation, BMI Body mass index, NRS2002 the Nutritional Risk Screening 2002, PG-SGA Patient-Generated Subjective Global Assessment, GLIM the Global Leadership Initiative on Malnutrition, GLIM-step1 One-step GLIM criteria, GLIM-step2 Two-step GLIM criteria. One-step GLIM criteria and two-step GLIM criteria represented different GLIM criteria with or without nutrition risk screening by NRS-2002, respectively, KPS Karnofsky Score, NLR Neutrophil-to-lymphocyte ratio, MAC Mid-arm circumference, TSF Triceps skinfold thickness, MAMC Mid-arm muscle circumference, CC Calf circumference (left calf)
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Nutrition Journal

ISSN: 1475-2891

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