Soft drink and non-caloric soft drink intake and their association with blood pressure: the Health Workers Cohort Study

Table 3 Association of soft drink and non-caloric soft drink intake with systolic and diastolic pressure (n = 1,324)

	Soft drink intake						Non-caloric soft drink intake
	Model 1^a			Model 2^b			Model 1^a			Model 2^b
Variable	Coefficient	CI 95%	P-value	Coefficient	CI 95%	P-value	Coefficient	CI 95%	P-value	Coefficient	CI 95%	P-value
Systolic blood pressure
Soft drinks	0.39	-0.98, 1.77	0.57	0.18	-1.23, 1.60	0.80	-0.82	-3.40,1.73	0.52	-0.93	-3.50, 1.64	0.48
Time	4.25	2.38, 6.11	< 0.001	10.36	6.73, 13.98	< 0.001	4.89	3.24, 6.55	< 0.001	11.46	7.96, 14.95	< 0.001
Soft drinks × Time	2.26	0.44, 4.09	0.02	2.08	0.21, 3.94	0.03	0.73	-1.42, 2.89	0.507	0.83	-1.34, 2.99	0.46
Diastolic blood pressure
Soft drinks	0.42	-0.52, 1.39	0.39	0.23	-0.74, 1.20	0.64	-0.05	-1.81, 1.71	0.95	-0.07	-1.85, 1.70	0.94
Time	5.19	3.91, 6.46	< 0.001	4.80	2.31, 7.28	< 0.001	5.83	4.70, 6.97	< 0.001	5.68	3.25, 8.10	< 0.001
Soft drinks × Time	2.02	0.77, 3.26	0.01	2.09	0.81, 3.36	0.001	0.08	-1.39, 1.57	0.90	0.15	-1.35, 1.65	0.84

^aModel 1: Soft drinks and BP, adjusted for baseline age centered to mean, sex centered
^bModel 2: Model 1 plus body mass index centered to mean, physical activity, smoking status, alcohol intake, education, energy intake and

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