Atopic heredity modifies the association between maternal vitamin D status in pregnancy and the risk of atopic disease in childhood: an observational study

Table 3 The relationship between maternal vitamin D intake and status with reported eczema at 5-years

	No reported atopic heredity			Reported atopic heredity
	OR	95% CI	P-value	OR	95% CI	P-value
T3 dietary vitamin D intake (µg/day)	1.141	1.011–1.288	0.032	0.879	0.725–1.066	0.191
Supplemental vitamin D intake in T1 and/or T3 (yes)	1.367	0.803–2.329	0.250	0.580	0.278–1.211	0.147
T1 25OHD (nmol/L)	0.997	0.985–1.009	0.632	1.003	0.986–1.020	0.712
T1 25OHD (nmol/L)
> 75 (ref)	1.0			1.0
< 50	0.703	0.314–1.573	0.391	1.213	0.372–3.955	0.749
50–75	1.014	0.582–1.764	0.962	0.838	0.397–1.769	0.643
T3 25OHD (nmol/L)	1.003	0.994–1.013	0.503	0.993	0.978–1.008	0.363
T3 25OHD (nmol/L)
> 75 (ref)	1.0			1.0
< 50	0.270	0.060–1.221	0.089	0.967	0.257–3.637	0.960
50–75	1.422	0.801–2.526	0.230	1.320	0.605–2.879	0.486

T1 early pregnancy, T3 late pregnancy, 25OHD 25-hydroxyvitamin D, OR Odds ratio, CI Confidence interval, ref reference category
Adjusted for maternal BMI in T1, level of education (university level, yes/no), ethnicity (northern Europe, yes/no), delivery mode (vaginal or Caesarean section) and tobacco use by either mother or other caregiver during pregnancy

ISSN: 1475-2891