Table 3 Alcohol consumption and the incidence of low eGFR in males and females

Males

 Incidence of CKD, n (%)

228 (3.1)

206 (3.3)

150 (3.5)

83 (4.7)

 IR per 1000PY

7.9

8.0

8.4

11.5

 Hazard ratio (95% CI)

  Unadjusted model

1.0 (reference)

0.99 (0.83–1.21)

0.97 (0.79–1.20)

1.32 (1.03–1.70) *

.172

  Adjusted model 1

1.0 (reference)

1.02 (0.84–1.23)

0.91 (0.73–1.12)

0.95 (0.73–1.24)

.432

  Adjusted model 2

1.0 (reference)

1.03 (0.85–1.24)

0.91 (0.73–1.12)

0.96 (0.73–1.25)

.454

  Adjusted model 3

1.0 (reference)

1.03 (0.85–1.24)

0.90 (0.73–1.11)

0.92 (0.71–1.20)

.342

Females

 Incidence of CKD, n (%)

120 (3.0)

69 (3.5)

38 (5.0)

28 (7.7)

 IR per 1000PY

8.3

10.0

13.0

20.1

 Hazard ratio (95% CI)

 Unadjusted model

1.0 (reference)

1.23 (0.91–1.65)

1.43 (0.99–2.06)

2.22 (1.47–3.36) *

 < .001

 Adjusted model 1

1.0 (reference)

1.23 (0.91–1.65)

1.21 (0.83–1.76) *

1.56 (1.01–2.39) *

.039

 Adjusted model 2

1.0 (reference)

1.22 (0.91–1.65)

1.19 (0.81–1.76)

1.65 (1.06–2.56) *

.030

 Adjusted model 3

1.0 (reference)

1.23 (0.91–1.65)

1.21 (0.83–1.79)

1.62 (1.04–2.53) *

.039