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Fig. 3 | Nutrition Journal

Fig. 3

From: Safety and efficacy of a probiotic-containing infant formula supplemented with 2’-fucosyllactose: a double-blind randomized controlled trial

Fig. 3

Comparison of the gut microbiota composition between the three feeding groups at baseline, 1, 2 and 3 months of age. BF, breastfed group; CG, control group; EG, experimental group. Redundancy analysis on the OTU level, assessing the effect of feeding on gut microbiota composition. OTUs were used as response data and feeding was explanatory data, the bacterial families that contributed most were plotted supplementary. The covariance attributed to confounders delivery mode and “at least 1 episode of antibiotics treatment before the 3 months visit” (only at 3 months of age) was first fitted by regression and then “partialled out” (removed) from the ordination. The (unadjusted) variation explained is indicated on the axes. a Baseline (≤ 0.5 months of age); variation explained by feeding was 0.8%, p = 0.002. b 1 month of age; variation explained by feeding was 2.8%, p = 0.002. c 2 months of age; variation explained by feeding was 3.3%, p = 0.002. d 3 months of age; Variation explained by feeding was 2.9%, p = 0.002. Sample size at each timepoint was: 71–81 in CG, 86–93 in EG and 25–29 in BF

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