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Table 3 General Characteristics of Participants With and Without TPOAb/TgAb/TRAb(+) - Without previous thyroid disease, n(%)

From: Iodine nutrition status and thyroid autoimmunity during pregnancy: a cross-sectional study of 4635 pregnant women

 

Pooled

Early pregnancy

Middle pregnancy

Late pregnancy

TPOAb/TgAb/TRAb(+)

TPOAb/TgAb/TRAb(−)

TPOAb/TgAb/TRAb(+)

TPOAb/TgAb/TRAb(−)

TPOAb/TgAb/TRAb(+)

TPOAb/TgAb/TRAb(−)

TPOAb/TgAb/TRAb(+)

TPOAb/TgAb/TRAb(−)

N

1225

2903

380

958

531

1197

314

748

Age, years

  ≥ 35*

154 (12.57)

393 (13.54)

49 (12.89)

139 (14.51)

62 (11.68)

143 (11.95)

43 (13.69)

111 (14.84)

Education status

  ≤ 9 years

447 (36.61)

941 (32.48)*

106 (27.97)

243 (25.47)

222 (42.05)

419 (35.03)*

119 (37.90)

279 (37.35)

 Senior high school

and college

293 (24.00)

753 (25.99)*

106 (27.97)

263 (27.57)

120 (22.73)

327 (27.34)*

67 (21.34)

163 (21.82)

 Bachelor’s degree and higher

481 (39.39)

1203 (41.53)*

167 (44.06)

448 (46.96)

186 (35.23)

450 (37.63)*

128 (40.76)

305 (40.83)

Occupation status

 Mental

1003 (81.88)

2286 (78.75)*

303 (79.74)

743 (77.56)

434 (81.73)

959 (80.12)

266 (84.71)

584 (78.07)

 Physical

222 (18.12)

617 (21.75)*

77 (20.26)

215 (22.44)

97 (18.27)

238 (19.88)

48 (15.29)

164 (21.93)

Family income per person last years, yuan

  < 100,000

274((20.28)

514 (17.77)*

58 (15.38)

136 (14.26)

117 (22.20)

226 (18.94)*

72 (22.93)

152 (20.38)

 100,000–200,000

525 (43.10)

1195 (41.31)*

153 (40.58)

405 (42.45)

233 (44.21)

492 (41.24)*

139 (44.27)

298 (39.95)

  ≥ 200,000

446 (36.52)

1184 (40.93)*

166 (44.03)

413 (43.29)

177 (33.59)

475 (39.82)*

103 (32.08)

296 (39.68)

Former smoker

35 (2.87)

70 (2.42)

10 (2.65)

25 (2.62)

17 (3.23)

31 (2.59)

8 (2.55)

14 (1.87)

Former drinker

133 (11.02)

293 (10.11)

34 (9.04)

96 (10.06)

63 (12.05)

129 (10.79)

36 (11.69)

68 (9.09)

First pregnancy

1488 (51.26)

634 (51.76)

466 (48.64)

186 (48.95)

288 (54.24)

636 (53.13)

160 (50.96)

386 (51.60)

Consumed iodine-rich food in the past 3 months

930 (75.92)

2383 (82.09)*

284 (74.74)

743 (77.56)

406 (76.46)

1011 (84.46)

240 (76.43)

629 (84.09)*

Consumed iodized nutritional supplements in the past 3 months

82 (6.69)

516 (17.77)*

27 (7.11)

134 (13.99)*

32 (6.03)

222 (18.55)*

23 (7.32)

160 (21.93)

Non-iodized salt

331 (27.02)

651 (22.43)*

102 (26.84)

222 (23.17)

146 (27.50)

263 (21.97)*

83 (26.43)

166 (22.19)

UIC, μg/L

124.57 (73.79–199.77)

143.67 (85.93–225.52)*

135.87 (73.39–219.33)

154.03 (91.40–246.95)*

128.93 (79.71–204.42)

142.23 (88.09–224.27)*

110.88 (64.30–186.60)

130.84 (71.29–201.67)*

Iodine from iodine-rich food and salt, median(q1-q3), μg

94.51 (25.26–180.00)

124.56 (44.98–221.53)*

69.48 (9.02–146.85)

104.86 (34.33–200.61)*

107.25 (42.55–185.07)

133.98 (51.56–228.61)*

109.44 (230.53–188.57)

137.60 (47.72–241.05)*

Iodine-intake groups, μg

  < 37.15

358 (29.22)

644 (22.18)*

148 (38.95)

243 (25.37)*

126 (23.73)

243 (20.30)*

84 (26.75)

158 (21.12)*

 37.15 ~ 113.54

334 (27.27)

713 (24.56)*

108 (28.42)

260 (27.14)*

146 (27.50)

288 (24.06)*

80 (25.48)

165 (22.06)*

 113.54 ~ 205.99

300 (24.49)

726 (25.01)*

68 (17.89)

224 (23.38)*

154 (29.00)

318 (26.57)*

78 (24.84)

184 (24.60)*

  ≥ 205.99

233 (19.02)

820 (28.25)*

56 (14.74)

231 (24.11)*

105 (19.07)

348 (29.07)*

72 (22.93)

241 (32.22)*

Hypothyroidism, %

30 (2.45)

63 (2.17)

13 (3.42)

20 (2.09)

10 (1.88)

24 (2.01)

7 (2.23)

19 (2.54)

  1. Data are summarized as the median values (inter-quartile range) for continuous variables, or as numbers with proportions for categorical variables. Urine iodine concentration, UIC
  2. *p < 0.05 versus the TPOAb/TgAb/TRAb(−) group