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Table 6 Effect of Curcuma longa extract (CLE) on the MOS 36-Item Short-Form Health Survey (SF-36) scoresa

From: Curcuma longa extract improves serum inflammatory markers and mental health in healthy participants who are overweight: a randomized, double-blind, placebo-controlled trial

  Change from baseline Repeated measures two-way ANOVA
Week 4 Week 8 Week 12 Group Time Interaction
Mean SD Mean SD Mean SD
Physical functioning (PF)
 Placebo 1.00 7.18 0.38 7.20 0.25 6.20 0.768 0.081 0.343
 CLE 0.77 5.91 1.71 5.61 0.64 7.18
Role physical (RP)
 Placebo 1.25 10.60 0.78 12.10 1.87 8.27 0.719 0.158 0.538
 CLE −0.65 12.40 0.16 9.36 2.24 10.08
Bodily pain (BP)
 Placebo −0.8 14.0 −2.0 14.3 −2.1 11.4 0.544 0.612 0.999
 CLE −2.4 14.9 −3.1 13.9 −3.7 15.6
General health (GH)
 Placebo −0.30 10.99 0.18 13.35 0.63 11.71 0.121 0.881 0.884
 CLE −3.08 9.73 −3.58 10.91 −3.05 12.80
Vitality (VT)
 Placebo −2.51 14.36 −0.94 11.88 1.71 10.49 0.692 0.040 0.734
 CLE −2.56 13.28 −1.32 11.99 −0.32 11.99
Social functioning (SF)
 Placebo −0.94 13.69 0.31 14.57 −0.63 13.56 0.438 0.221 0.749
 CLE 0.32 18.02 3.95 14.85 1.92 12.35
Role emotional (RE)
 Placebo 0.63 11.99 0.84 12.20 1.04 12.27 0.924 0.648 0.850
 CLE −0.21 13.04 0.88 11.76 1.49 11.78
Mental health (MH)
 Placebo −3.63 10.50 −3.38 11.29 −1.75 9.37 0.032 0.127 0.416
 CLE −0.90 9.86 2.89* 10.24 1.92 10.68
Physical component summary (PCS)
 Placebo 1.22 4.85 0.77 4.66 0.54 3.67 0.574 0.836 0.491
 CLE 0.23 4.97 0.28 4.02 0.52 4.63
Mental component summary (MCS)
 Placebo −1.76 5.10 −1.18 5.33 −0.38 4.39 0.618 0.144 0.766
 CLE −1.21 5.72 −0.10 4.55 −0.37 5.24
  1. aValues represent the means and standard deviations for n = 40 (placebo group) or n = 39 (CLE group). *p < 0.05: Significant difference from the placebo group by repeated measures two-way ANOVA, followed by the two-tailed unpaired Student’s t test when variance was homogeneous or the Aspin-Welch t test when variance was heterogeneous