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Table 1 Characteristics of the single-nucleotide polymorphisms associated with serum 25-hydroxyvitamin D, calcium, and parathyroid hormone levels and their associations with coronary artery disease in patients with diabetes

From: The impact of serum 25-hydroxyvitamin D, calcium, and parathyroid hormone levels on the risk of coronary artery disease in patients with diabetes: a Mendelian randomization study

Traits SNP Chr Nearby gene EA OA EAF 25OHD/Calcium/PTH CAD in patients with diabetes
Beta SE P Beta SE P
25OHD rs3755967 4 GC C T 0.72 0.089 0.002 4.74E-343 0.032 0.029 0.274
25OHD rs12785878 11 DHCR7 T G 0.75 0.036 0.002 3.80E-62 -0.055 0.033 0.090
25OHD rs10741657 11 CYP2R1 A G 0.40 0.031 0.002 2.05E-46 -0.001 0.027 0.972
25OHD rs17216707 20 CYP24A1 T C 0.79 0.026 0.003 8.14E-23 -0.033 0.035 0.344
25OHD rs10745742 12 AMDHD1 T C 0.40 0.017 0.002 1.88E-14 -0.019 0.028 0.495
25OHD rs8018720 14 SEC23A G C 0.18 0.017 0.003 4.72E-09 0.019 0.034 0.586
Calcium rs1801725 3 CASR T G 0.15 0.071 0.004 8.90E-86 0.052 0.039 0.186
Calcium rs1570669 20 CYP24A1 G A 0.34 0.018 0.003 9.10E-12 -0.001 0.028 0.981
Calcium rs1550532 2 DGKD C G 0.31 0.018 0.003 8.20E-11 -0.017 0.028 0.545
Calcium rs7481584 11 CARS G A 0.70 0.018 0.003 1.20E-10 -0.004 0.030 0.904
Calcium rs780094 2 GCKR T C 0.42 0.017 0.003 1.30E-10 0.085 0.028 0.002
Calcium rs7336933 13 DGKH G A 0.85 0.022 0.004 9.10E-10 -0.021 0.037 0.568
Calcium rs10491003 10 GATA3 T C 0.09 0.027 0.005 4.80E-09 -0.013 0.046 0.784
PTH rs6127099 20 CYP24A1 T A 0.34 0.070 0.003 2.40E-72 0.021 0.030 0.494
PTH rs4074995 5 RGS14 G A 0.71 0.030 0.003 3.30E-23 0.029 0.030 0.337
PTH rs219779 21 CLDN14 G A 0.75 0.040 0.003 8.90E-22 -0.017 0.030 0.582
PTH rs4443100 22 RTDR1 G C 0.32 0.020 0.003 4.10E-11 -0.025 0.029 0.390
PTH rs73186030 3 CASR T C 0.14 0.030 0.004 1.20E-09 0.051 0.039 0.198
  1. SNP indicates single-nucleotide polymorphism, Chr chromosome, EA effect allele, OA other allele, EAF effect allele frequency, 25OHD 25-hydroxyvitamin D, PTH parathyroid hormone, CAD coronary artery disease, SE standard error