Table 6 Modelled estimates of differences in apolipoprotein, lipoproteins and lipids between intervention and controla
|
Intervention (n = 42) Mean Change (95% CIs) |
Control (n = 43) Mean Change (95% CIs) |
Difference between dietary periodsb | 95% CIs | P | |
|---|---|---|---|---|---|
| Apolipoprotein concentrations (mg/dL) | |||||
| Apo-A1 | 2.782 (− 1.491, 7.054) | 1.111 (− 3.104, 5.327) | 1.670 | − 3.505, 6.846 | 0.517 |
| Apo-B100 | − 0.325 (− 3.758, 3.108) | 4.130 (0.741, 7.520) | − 4.455 | −8.331, − 0.578 | 0.026 |
| Apo-B100/Apo-A1 | − 0.016 (− 0.039, 0.007) | 0.022 (0.000, 0.045) | − 0.038 | − 0.066, − 0.011 | 0.007 |
| Particle numbers (nmol/L) | |||||
| VLDL | −5.750 (− 15.270, 3.771) | 4.835 (− 4.535, 14.205) | − 10.585 | − 23.951, 2.782 | 0.119 |
| IDL | −2.813 (− 9.383, 3.757) | 7.429 (0.958, 13.899) | − 10.241 | − 18.699, − 1.783 | 0.019 |
| LDL | 7.210 (− 53.413, 67.833) | 62.424 (2.563, 122.285) | −55.214 | −123.396, 12.968 | 0.109 |
| Triglycerides in lipoprotein particles (mg/dL) | |||||
| VLDL | −11.762 (− 19.999, −3.526) | 5.072 (− 3.038, 13.182) | − 16.834 | −28.404, − 5.264 | 0.005 |
| IDL | −2.022 (− 3.448, − 0.595) | 1.068 (− 0.337, 2.473) | −3.090 | −5.092, − 1.088 | 0.003 |
| LDL | 0.054 (− 0.840, 0.949) | 0.870 (− 0.011, 1.750) | − 0.815 | − 1.976, 0.345 | 0.163 |
| HDL | −0.171 (− 0.726, 0.385) | 0.586 (0.039, 1.133) | − 0.757 | − 1.530, 0.016 | 0.055 |
| Cholesterol in HDL particles (mg/dL) | |||||
| HDL-1 | 2.461 (0.922, 4.001) | −0.625 (− 2.145, 0.894) | 3.087 | 1.303, 4.871 | 0.001 |
| HDL-2 | 0.327 (−0.086, 0.741) | −0.181 (− 0.590, 0.227) | 0.509 | 0.063, 0.955 | 0.027 |
| HDL-3 | 0.045 (−0.339, 0.430) | −0.012 (− 0.390, 0.367) | 0.057 | −0.459, 0.573 | 0.824 |
| HDL-4 | −0.223 (− 0.976, 0.530) | 0.282 (− 0.459, 1.023) | −0.505 | −1.524, 0.513 | 0.320 |