Diet intervention improves cardiovascular profile in patients with rheumatoid arthritis: results from the randomized controlled cross-over trial ADIRA

Table 4 Modelled estimates of differences in blood lipids and blood pressure between intervention and control^a

	Intervention (n = 45) Mean Change (95% CIs)	Control (n = 46) Mean Change (95% CIs)	Difference between dietary periods^b	95% CIs	P
Total Cholesterol (mmol/L) ^c	−0.015 (− 0.187, 0.157)	0.096 (− 0.073, 0.265)	− 0.111	− 0.315, 0.093	0.279
LDL Cholesterol (mmol/L) ^c	− 0.074 (− 0.220, 0.072)	0.079 (− 0.065, 0.223)	− 0.153	−0.322, 0.016	0.075
HDL Cholesterol (mmol/L) ^c	0.047 (− 0.033, 0.128)	− 0.027 (− 0.107, 0.053)	0.074	0.000, 0.148	0.049
Triglycerides (mmol/L) ^c	−0.114 (− 0.211, − 0.018)	0.078 (− 0.017, 0.173)	− 0.192	− 0.328, − 0.057	0.007
Non-HDL Cholesterol (mmol/L) ^c	− 0.063 (− 0.211, 0.085)	0.124 (− 0.023, 0.270)	− 0.187	− 0.373, − 0.001	0.049
SBP (mmHg) ^d	− 1.709 (−5.824, 2.407)	− 2.611 (−6.669, 1.447)	0.902	−3.915, 5.720	0.707
DBP (mmHg) ^d	−2.154 (−4.282, − 0.027)	−4.041 (− 6.134, − 1.948)	1.886	−1.098, 4.871	0.212

^aParticipants completing at least one dietary period (n = 47). LDL Low Density Lipoprotein, HDL High Density Lipoprotein, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure
^bIntervention – Control, post period values
^cAnalysed by use of a linear mixed model with period, treatment, sequence and baseline value as fixed effects and subject as random effect adjusted for sex
^dAnalysed by use of a linear mixed model with period, treatment, sequence and baseline value as fixed effects and subject as random effect

ISSN: 1475-2891