Regular consumption of soft drinks is associated with type 2 diabetes incidence in Mexican adults: findings from a prospective cohort study

Table 3 Risk of Type 2 Diabetes according to categories of soft drinks intake in participants from HWCS stratified by family history of diabetes (yes/no)^a

	Consumption level
	< 1/week	1–4 /week	> 5/week	p _trend^a
Subjects without family history of diabetes (n = 582)
n	147	303	132
Cases of type 2 diabetes (n = 25)	7	12	6
Person-years	969.4	2032.2	862.6
Incidence rate (per 1000)	7.2 (3.4–15.1)	5.9 (3.4–10.4)	7.0 (3.1–15.5)
Multivariate-adjusted², HR (95% CI)^b	Ref.	0.67 (0.25–1.79)	0.66 (0.20–2.16)	0.674
Subjects with family history of diabetes (n = 757)
n	189	402	166
Cases of type 2 diabetes (n = 74)	10	38	26
Person-years	1233.4	2673.9	1078.5
Incidence rate (per 1000)	8.1 (4.4–15.1)	14.2 (10.3–19.5)	24.0 (16.1–35.4)
Multivariate-adjusted, HR (95% CI)^b	Ref.	1.49 (0.73–3.07)	2.3 (1.04–5.17)	0.037

Abbreviations: HWCS Health Workers Cohort Study, IQR Interquartile range, HR Hazard risk, CI Confidence interval
P for overall interaction = 0.4285
^a A linear trend in the HR for each of the soft drinks categories was evaluated by including a continuous variable in the model representing the median values of each of soft drinks intake
^b Adjusted for baseline covariates: age centered, sex, total energy intake, physical activity, smoking status, alcohol intake at baseline (in tertiles) and level of education

ISSN: 1475-2891