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Table 2 Association between plasma PUFA and telomere length in the individual datasets and after meta-analysis

From: Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population

  SCHS_CAD cases SCHS_CAD control Meta-analysis
N = 711 N = 638 N = 1349
beta se p beta se p beta se p Qp-value
n6:n3 ratio −0.008 0.009 0.362 −0.024 0.009 0.011 −0.015 0.006 0.018 0.202
n-3 fatty acid 0.005 0.009 0.535 0.025 0.009 0.007 0.014 0.006 0.024 0.114
18:3 (n-3) ALA 0.010 0.009 0.251 −0.008 0.009 0.403 0.002 0.006 0.769 0.164
20:5 (n-3) EPA 0.010 0.009 0.240 0.023 0.009 0.014 0.016 0.006 0.011 0.294
22:6 (n-3) DHA 0.004 0.009 0.622 0.029 0.009 0.003 0.015 0.006 0.017 0.054
n-6 fatty acid −0.002 0.002 0.260 4.92× 10−4 0.002 0.806 −0.001 0.001 0.503 0.348
18:2(n-6) LA −0.002 0.002 0.408 1.47× 10−4 0.002 0.943 −0.001 0.001 0.570 0.544
18:3(n-6) GLA 0.012 0.009 0.187 0.003 0.010 0.772 0.008 0.007 0.239 0.507
20:3(n-6) DGLA 1.74 × 10−4 0.009 0.984 0.002 0.010 0.802 0.001 0.007 0.855 0.862
20:4(n-6) AA −0.004 0.005 0.396 0.003 0.005 0.636 −0.001 0.004 0.774 0.353
  1. ALA α-Linolenic acid; EPA Eicosapentaenoic acid; DHA Docosahexaenoic acid; LA Linoleic acid; GLA γ-Linolenic acid; DGLA Dihomo-γ-linolenic acid; AA Arachidonic acid; MAF Minor allele frequency. Qp-value Cochran’s Q heterogeneity measure
  2. Beta showed the effect of each percentage change on the change of telomere length (T/S ratio) for n-6 fatty acid, LA and AA, and 1-SD change in the fatty acid in the change of telomere length (T/S ratio) for n6:n3 ratio, n-3 fatty acid, ALA, EPA, DHA GLA and DGLA