Nutrition Journal

Table 2 Association between plasma PUFA and telomere length in the individual datasets and after meta-analysis

From: Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population

	SCHS_CAD cases			SCHS_CAD control			Meta-analysis
	N = 711			N = 638			N = 1349
	beta	se	p	beta	se	p	beta	se	p	Q_p-value
n6:n3 ratio	−0.008	0.009	0.362	−0.024	0.009	0.011	−0.015	0.006	0.018	0.202
n-3 fatty acid	0.005	0.009	0.535	0.025	0.009	0.007	0.014	0.006	0.024	0.114
18:3 (n-3) ALA	0.010	0.009	0.251	−0.008	0.009	0.403	0.002	0.006	0.769	0.164
20:5 (n-3) EPA	0.010	0.009	0.240	0.023	0.009	0.014	0.016	0.006	0.011	0.294
22:6 (n-3) DHA	0.004	0.009	0.622	0.029	0.009	0.003	0.015	0.006	0.017	0.054
n-6 fatty acid	−0.002	0.002	0.260	4.92× 10⁻⁴	0.002	0.806	−0.001	0.001	0.503	0.348
18:2(n-6) LA	−0.002	0.002	0.408	1.47× 10⁻⁴	0.002	0.943	−0.001	0.001	0.570	0.544
18:3(n-6) GLA	0.012	0.009	0.187	0.003	0.010	0.772	0.008	0.007	0.239	0.507
20:3(n-6) DGLA	1.74 × 10⁻⁴	0.009	0.984	0.002	0.010	0.802	0.001	0.007	0.855	0.862
20:4(n-6) AA	−0.004	0.005	0.396	0.003	0.005	0.636	−0.001	0.004	0.774	0.353

ALA α-Linolenic acid; EPA Eicosapentaenoic acid; DHA Docosahexaenoic acid; LA Linoleic acid; GLA γ-Linolenic acid; DGLA Dihomo-γ-linolenic acid; AA Arachidonic acid; MAF Minor allele frequency. Q_p-value Cochran’s Q heterogeneity measure
Beta showed the effect of each percentage change on the change of telomere length (T/S ratio) for n-6 fatty acid, LA and AA, and 1-SD change in the fatty acid in the change of telomere length (T/S ratio) for n6:n3 ratio, n-3 fatty acid, ALA, EPA, DHA GLA and DGLA

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ISSN: 1475-2891

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