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Table 2 Quality of life in breast cancer patients’ before and after intervention in KD group and control group as measured by the EORTC QLQ-C30a

From: Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: a randomized controlled clinical trial

Functioninga KD Control MD (95% CI) p-value
Physical functioning
 Week 0 89 ± 11a 76 ± 20 13 (4.4,21.7) 0/004
 Week 12 78 ± 19 68 ± 20 9.9 (−.7,20) 0/06
p-value 0/04 0/05   
Role functioning
 Week 0 86 ± 16 79 ± 28 7.2 (−4.9,19.4) 0/24
 Week 12 75 ± 25 66 ± 29 8.9 (−6,23) 0/23
p-value 0/10 0/02   
Cognitive functioning
 Week 0 85 ± 16 71 ± 28 13.7 (1,26) 0/03
 Week 12 75 ± 19 72 ± 21 5.5(−8,14) 0/59
p-value 0/03 1   
Emotional functioning
 Week 0 67 ± 21 66 ± 21 1.1 (−9.9,12.2) 0/84
 Week 12 62 ± 23 60 ± 21 2(−10,14) 0/73
p-value 0/34 0/11   
Social functioning
 Week 0 94 ± 17 93 ± 17 0.36(−8.8,9.5) 0/93
 Week 12 91 ± 17 87 ± 17 3.5(−4.6,5.9) 0/45
p-value 0/38 0/02   
Global quality of life
 Week 0 68 ± 16 65 ± 16 3.6 (−5.1,12.3) 0/41
 Week 12 70 ± 20 62 ± 20 8.1(−5.7,3.3) 0/16
p-value 0/64 0/49   
  1. After adjusting for baseline value and chemotherapy status no significant differences were observed
  2. Student t-test was used to compare the continuous variables between the two groups. Paired sample t-test was used to compare the continuous variables within the two groups
  3. Data shown as mean and SD
  4. aThe higher values indicate higher level of functioning and quality of life