Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: a randomized controlled clinical trial

Table 2 Quality of life in breast cancer patients’ before and after intervention in KD group and control group as measured by the EORTC QLQ-C30^a

Functioning^a	KD	Control	MD (95% CI)	p-value
Physical functioning
Week 0	89 ± 11^a	76 ± 20	13 (4.4,21.7)	0/004
Week 12	78 ± 19	68 ± 20	9.9 (−.7,20)	0/06
p-value	0/04	0/05
Role functioning
Week 0	86 ± 16	79 ± 28	7.2 (−4.9,19.4)	0/24
Week 12	75 ± 25	66 ± 29	8.9 (−6,23)	0/23
p-value	0/10	0/02
Cognitive functioning
Week 0	85 ± 16	71 ± 28	13.7 (1,26)	0/03
Week 12	75 ± 19	72 ± 21	5.5(−8,14)	0/59
p-value	0/03	1
Emotional functioning
Week 0	67 ± 21	66 ± 21	1.1 (−9.9,12.2)	0/84
Week 12	62 ± 23	60 ± 21	2(−10,14)	0/73
p-value	0/34	0/11
Social functioning
Week 0	94 ± 17	93 ± 17	0.36(−8.8,9.5)	0/93
Week 12	91 ± 17	87 ± 17	3.5(−4.6,5.9)	0/45
p-value	0/38	0/02
Global quality of life
Week 0	68 ± 16	65 ± 16	3.6 (−5.1,12.3)	0/41
Week 12	70 ± 20	62 ± 20	8.1(−5.7,3.3)	0/16
p-value	0/64	0/49

After adjusting for baseline value and chemotherapy status no significant differences were observed
Student t-test was used to compare the continuous variables between the two groups. Paired sample t-test was used to compare the continuous variables within the two groups
Data shown as mean and SD
^aThe higher values indicate higher level of functioning and quality of life

ISSN: 1475-2891