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Fig. 3 | Nutrition Journal

Fig. 3

From: Gut microbiota-associated metabolite trimethylamine N-Oxide and the risk of stroke: a systematic review and dose–response meta-analysis

Fig. 3

Forest plots of weighted mean difference (WMD) with 95% confidence interval (CI) for the circulating levels of trimethylamine N-oxide (TMAO) in stroke versus non-stroke patients. As shown in Fig. 3, four studies were included in the analysis. The result showed that mean TMAO concentrations was 2.20 μmol/L higher in patients with stroke compared with non-stroke controls (WMD: 2.20, 95% CI: 1.21–3.18, P < 0.001), with a significant heterogeneity (I2 = 99.7%, P < 0.001). I2 represents the degree of heterogeneity

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