Fig. 2From: Gut microbiota-associated metabolite trimethylamine N-Oxide and the risk of stroke: a systematic review and dose–response meta-analysisForest plot presenting odds ratio (OR) for stroke in the highest versus the lowest category of trimethylamine N-oxide (TMAO) concentrations. As shown in Fig. 2, five studies were included in the analysis of TMAO concentrations and risk of stroke. The result showed that being in the highest category of TMAO is associated with 68% increased odds of stroke (OR: 1.67, 95% confidence interval (CI): 0.86–3.24, P = 0.04), with a significant heterogeneity (I2 = 84.9, P < 0.001). I2 represents the degree of heterogeneityBack to article page