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Table 2 Subgroup analyses of mean change in total cholesterol, LDL cholesterol, HDL cholesterol and triglyceride

From: Effect of green tea consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials

Subgroup Change in total cholesterol Change in LDL cholesterol Change in HDL cholesterol Change in Triglyceride
Trials (n) Net change
(95% CI) (mg/dl)
I2 Trials (n) Net change
(95% CI) (mg/dl)
I2 Trials (n) Net change
(95% CI) (mg/dl)
I2 Trials (n) Net change
(95%CI) (mg/dl)
I2
Type of intervention
 Green tea beverage 9 −2.80(−5.43, −0.16) 10% 8 −2.61(− 5.49, 0.27) 0% 8 − 0.84(− 1.74, 0.06) 17% 9 − 0.77(− 12.15, 10.61) 42%
 Green tea capsule 22 −5.41(−7.46, −3.37) 21% 21 − 5.28(− 7.44, − 3.12) 36% 21 0.73(− 0.07, 1.54) 25% 20 − 4.62(− 10.52, 1.27) 62%
Duration
  ≥ 12 weeks 15 −5.59(−8.66, − 2.51) 23% 14 − 4.04(− 7.13, − 0.94) 39% 15 0.92(− 0.12, 1.96) 39% 15 −9.03(− 17.92, − 0.15) 72%
  < 12 weeks 16 − 4.05(− 6.05, − 2.06) 21% 15 − 4.91(− 7.06, − 2.75) 20% 14 − 0.42(− 1.26, 0.41) 20% 14 0.77(− 3.83, 5.36) 3%
Country
 Western 16 − 4.79(− 6.89, − 2.70) 24% 14 −5.07(− 7.25, − 2.89) 23% 14 −0.25(− 1.18, 0.68) 43% 13 − 3.11(− 10.72, 4.49) 66%
 Asian 15 −4.50(− 7.58, − 1.43) 27% 15 −3.98(− 6.87, − 1.09) 34% 15 0.79(− 0.13, 1.71) 12% 16 −4.52(− 11.50, 2.46) 42%
Catechins dose
  ≥ 642 mg/dl 16 −4.44(− 6.52, − 2.36) 22% 15 −3.53(− 6.14, − 0.92) 36% 16 −0.34(− 1.23, 0.55) 26% 15 −1.89(− 7.70, 3.93) 41%
  < 642 mg/dl 15 −5.14(− 8.17, − 2.11) 29% 14 −5.52(− 7.93, − 3.10) 20% 13 0.92(− 0.11, 1.95) 39% 14 −5.75(− 14.99, 3.49) 66%
Caffeine
 With caffeine 12 −4.28(− 7.61, − 0.96) 0% 9 − 2.33(− 5.69, 1.04) 16% 10 −0.11(− 0.90, 0.68) 0% 11 − 1.20(− 10.48, 8.08) 42%
 Without caffeine 13 −4.27(− 6.44, − 2.10) 42% 14 −4.81(− 7.04, − 2.57) 38% 12 −0.17(−1.16, 0.82) 43% 11 −1.18(− 8.07, 5.71) 57%
unclear 6 −8.17(−13.84, − 2.49) 12% 6 −8.15(−13.08, −3.22) 0% 7 1.72(0.00, 3.44) 29% 7 −11.22(−22.82, 0.38) 60%
Study design
 Parallel 28 −5.04(− 7.03, −3.04) 29% 26 −4.64(− 6.63, −2.64) 34% 26 0.37(−0.38, 1.11) 40% 26 −4.47(− 10.10, 1.15) 60%
 Crossover 3 −2.98(− 6.11, 0.15) 0% 3 −4.07(− 7.88, −0.26) 0% 3 −0.56(− 2.34, 1.22) 0% 3 1.03(−9.02, 11.08) 0%
Health status
 Overweight or obese 19 −3.86(−6.11, −1.61) 19% 18 −3.97(−6.75, − 1.18) 39% 19 0.34(−0.62, 1.30) 49% 18 −7.63(−15.53, 0.28) 58%
 Normal weight 12 −5.59(−8.07, −3.10) 22% 11 −5.46(−7.23, −3.69) 0% 10 0.17(−0.73, 1.08) 0% 11 2.56(−1.57, 6.69) 7%
Study Bias
 Low risk 9 −5.13(−9.15, −1.11) 41% 9 −4.49 (−7.64, −1.34) 33% 9 0.12(−0.90, 1.15) 0% 8 1.23(−9.66, 12.13) 59%
 Some concerns 2 −2.77(−6.27, 0.74) 0% 2 −4.67(−9.59, 0.25) 0% 2 −1.07(−4.30, 2.15) 0% 2 −0.60(−10.78, 9.57) 0%
 High risk 20 −4.53(−6.66, −2.41) 18% 18 −4.56 (−7.07, −2.05) 36% 18 0.39(−0.55, 1.33) 50% 19 −6.33(−12.83, 0.16) 54%