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Table 1 Characteristics of 31 included randomized controlled trials

From: Effect of green tea consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials

Reference Study design No.of subjects (M/F) Age (y) Country or Region Population Duration Tea group Control group
Basu 2011 [23] P 25(5/20) 43.7 ± 3 USA Obese, 8wk decaffeinated GTE beverage (928 mg catechins) Placebo (water)
Bogdanski 2012 [24] P 56(28/28) 50.4 ± 8 Poland Obese 3mo GTE capsule(208 mg EGCG) placebo (cellulose)
Brown 2009 [25] P 88(88/0) 51.4 ± 6.4 UK Overweight/obese 8wk decaffeinated GTE capsule (800 mg EGCG) Placebo (lactose)
Brown 2011 [26] C 66(66/0) 49.5 ± 5.6 UK Overweight/obese 6wk decaffeinated GTE capsule (800 mg catechins) Placebo (lactose)
Chan 2006 [27] P 34(0/34) 34.8 ± 4.2 China obese 3mo GTE capsule (661.3 mg cathchins, 152.8 caffeine) placebo
Chen 2016 [28] P 77(0/77) 44.5 ± 11.5 Taiwan Obese 12wk decaffeinated GTE capsule (1344 catechins) placebo (cellulose)
Diepvens 2006 [29] P 46(0/46) 41.6 ± 10 Netherlands Overweight 12wk GTE capsule (1125 mg catechins, 225 mg caffeine) placebo
Frank 2009 [30] P 33(33/0) 40.5 ± 10 UK Overweight 3wk GTE capsule (672 mg catechins, 114 mg caffeine) Placebo (matched with caffeine)
Freese 1999 [31] P 20(0/20) 23–50 Finland Healthy 4wk GTE capsule (630 mg cathchins,150 caffeine) Placebo (saccharose, microcrystalline, cocoa)
Fukino 2008 [32] C 60(49/11) 53.6 ± 8.2 Japan Diabetes, overweight 2mo GTE beverage (456 mg catechins, 102 mg caffeine) No intervention
Hsu 2008 [33] P 78(0/78) 43.5 ± 12 Taiwan Obese 3mo GTE capsule (613.5 mg cathchins, 27.3 caffeine) Placebo
Hsu 2011 [34] P 68(24/44) 51.4 ± 9.2 Taiwan Obese, Diabetes 16wk decaffeinated GTE capsule (1344 catechins) placebo (cellulose)
Huang 2018 [35] C 73(0/73) 55 ± 9.5 Taiwan Overweight/obese 6wk decaffeinated GTE capsule (1344 catechins) Placebo (microcrystalline cellulose)
Kafeshani 2017 [36] P 32(32/0) 21 ± 2 Iran Healthy 6wk GTE capsule (240 mg catechins) placebo (maltodextrin)
Lee 2016 [37] P 77(66/11) 62 ± 12 Taiwan Chronic Stable Angina, overweight 6wk decaffeinated GTE capsule (600 mg polyphenol) placebo
Liu 2014 [38] P 77(32/45) 54.3 ± 7 Taiwan Diabetes, obese 16wk decaffeinated GTE capsule (1344 catechins) placebo (cellulose)
Lu 2016 [39] P 64(0/64) 29 ± 10 Taiwan Acne 4wk decaffeinated GTE capsule (1344 catechins) placebo (cellulose)
Maki 2009 [40] P 128(67/61) 48 ± 9 USA Obese 12w GTE beverage (625 mg catechins, 39 mg caffeine) Placebo (matched with caffeine)
Maron 2003 [41] P 240(100/140) 54.7 ± 11 China Hypercholesterolemia, overweight 12wk GTE capsule (150 mg cathchins) Placebo (inertingredients)
Mielgo-Ayuso 2014 [42] P 83(0/83) 18–49 Spain Obese 12wk 300 mg EGCG Placebo (lactose)
Miyazaki 2013 [43] P 52(20/32) 69.1 ± 5.9 Japan Not obese 14wk GTE beverage (630.9 mg catechins, 77 mg caffeine) GTE beverage (88.7 mg catechins and 82.4 mg caffeine)
Nagao 2007 [44] P 240(140/100) 41.7 ± 9.9 Japan Overweight 12wk GTE beverage (582.8 mg catechins, 72.3 caffeine) GTE beverage (96 mg catechins, matched with caffeine)
Nagao 2009 [45] P 43(18/25) 63.9 ± 2 Japan Diabetes, overweight 12wk GTE beverage (582.8 mg catechins, 72.3 caffeine) GTE beverage (96 mg catechins, matched with caffeine)
Nantz 2009 [46] P 111 (46/65) 29 ± 10.9 USA Healthy 3mo decaffeinated GTE capsule (320 catechins) Placebo (maltodextrin)
Princen-a 1998 [47] P 30 33.5 ± 13 Netherlands Healthy 4wk GTE beverage (851.7 mg catechins) Placebo (mineral water)
Princen-b 1998 [47] P 28 34 ± 12 Netherlands Healthy 4wk GTE capsule (2488.7 mg catechins) Placebo (mineral water)
Samavat 2016 [48] P 936(0/936) 60 ± 5 USA Healthy 12mo decaffeinated GTE capsule (1315 mg catechins) Placebo (maltodextrin and cellulose)
Sone 2011 [49] P 51(18/33) 45.7 ± 13.6 Japan Healthy 9wk GTE beverage (400 mg catechins, 105 mg caffeine) GTE beverage (100 mg catechins; 80 mg caffeine)
Suliburska 2012 [50] P 46(23/23) 50.4 ± 8.3 Poland Obese 3mo GTE capsule (208 mg EGCG) placebo (cellulose)
Tadayon 2018 [51] P 79(0/79) 53.3 ± 4 Iran Overweight/ obese 4wk 800 mg GTE capsule (80-94polyphenol) placebo
Venkatakrishnan 2018 [52] P 40 NA Taiwan Healthy 12wk GTE beverage (780.6 mg of catechin,106.7 caffeine) placebo
Wu-a 2012 [53] P 69(0/69) 58.7 ± 6.4 USA Healthy 8wk decaffeinated GTE capsule (536 mg catechins) placebo
Wu-b 2012 [53] P 66(0/66) 59.9 ± 7.9 USA Healthy 8wk decaffeinated GTE capsule (1072 mg catechins) placebo
  1. GTE green tea extract, P parallel trial, C crossover trial, wk. week, mo month, NA not available