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Table 4 Weighted odds ratios (95% confidence intervals) for score on Digit Symbol Substitution test across tertiles of dietary ω-3 and ω-6 fatty acids intake and ω-6: ω-3 ratio, NHANES 2011–2014 (N = 2496)

From: Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: National Health and nutrition examination Survey (NHANES) 2011–2014

 

Case/Participants

Crude1

Model 11

Model 21

ω-3 (mg/kcal/day)

 <0.727

243/832

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

 0.727 to <1.04

232/832

0.88(0.61–1.24)

0.86(0.60–1.21)

0.93(0.57–1.51)

  ≥ 1.04

171/832

0.63(0.43–0.91) *

0.62(0.42–0.88) *

0.59(0.37–0.92) *

ω-6 (mg/kcal/day)

 <6.538

254/832

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

 6.538 to <8.848

235/832

0.76(0.56–1.01)

0.76(0.57–1.02)

0.78(0.51–1.18)

  ≥ 8.848

157/832

0.47(0.32–0.68) **

0.49(0.33–0.71) **

0.50(0.34–0.75) **

ω-6: ω-3 ratio

 <7.684

223/832

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

 7.684 to <9.462

228/832

1.05(0.73–1.51)

1.06(0.74–1.52)

1.01(0.66–1.57)

  ≥ 9.462

195/832

0.71(0.53–0.93) *

0.74(0.55–0.99) *

0.86(0.54–1.36)

  1. 1Calculated using binary logistic regression
  2. Model 1 adjusted for age and gender
  3. Model 2 adjusted for age and gender, race, educational level, marital status, income, BMI, recreational activity, work activity, drinking status, hypertension, diabetes and stroke
  4. *p < 0.05; **p < 0.01