| Variables | Cinnamon Group, n = 20 | Placebo Group, n = 19 | P** |
|---|
| Before Treatment |
| hs-CRP (ng/ml) | 4392.80 ± 3969.60 | 6209.52 ± 4217.05 | 0.06 |
| TNF-α (pg/ml) | 28.72 ± 35.52 | 17.12 ± 9.02 | 0.21 |
| IL-6 (pg/ml) | 6.08 ± 2.40 | 6.33 ± 2.66 | 0.76 |
| NF-kB (ng/ml) | 6.02 ± 15.74 | 1.96 ± 2.73 | 0.34 |
| SIRT1 (ng/ml) | 5.54 ± 6.96 | 3.34 ± 0.29 | 0.13 |
| After Treatment |
| hs-CRP (ng/ml) | 3139.45 ± 2732.06 | 4155.42 ± 3422.95 | 0.29 |
| Differences | - 1253.35 ± 2992.23 | - 2054.10 ± 3228.78 | 0.21 |
| P* | 0.22 | 0.008 | |
| TNF-α (pg/ml) | 28.88 ± 26.97 | 17.60 ± 8.56 | 0.27 |
| Differences | - 1.84 ± 12.20 | 0.47 ± 8.60 | 0.81 |
| P* | 0.90 | 0.84 | |
| IL-6 (pg/ml) | 5.68 ± 1.33 | 6.09 ± 1.98 | 0.52 |
| Differences | −0.40 ± 2.23 | - 0.23 ± 2.82 | 0.84 |
| P* | 0.60 | 0.85 | |
| NF-kB (ng/ml) | 3.48 ± 6.45 | 0.85 ± 0.58 | 0.02 |
| Differences | - 2.53 ± 10.80 | - 1.11 ± 2.49 | 0.26 |
| P* | 0.69 | 0.055 | |
| SIRT1 (ng/ml) | 6.16 ± 12.13 | 3.62 ± 1.26 | 0.51 |
| Differences | 0.62 ± 5.82 | 0.28 ± 1.27 | 0.23 |
| P* | 0.39 | 0.38 | |
- Data are presented as mean ± standard deviation (SD) for continuous variables. * P was applied for the comparisons among groups, with the use of Student’s t-test for continuous variables, Mann–Whitney test for variables with non-normal distribution. ** P was used for the comparisons between groups, with use of paired t-test for continuous variables, Wilcoxon test for variables with non-normal distribution. Difference is significant at P < 0.050. Abbreviations: hs-CRP high-sensitive C-Reactive Protein, TNF-α Tumor Necrosis Factor-alpha, IL-6 Interleukine-6, NF-kB Nuclear factor-Kappa B, SIRT1 Sirtuin-1
