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Table 1 Anthropometric, clinic and metabolic parameters in well nourished and disease-related malnutrition subjects according to the presence of inflammation

From: Malnutrition impairs mitochondrial function and leukocyte activation

 

NN

(n = 34)

DRM-I

(n = 21)

DRM + I

(n = 28)

p value

Age (years)

60.0  ±  16.2

51.1 ±  23.5

65.8 ±  13.4#

0.030

Gender (% men)

23.5

14.3

57.1

0.002

Weight (Kg)

67.9  ±  15.6

45.8 ±  10.3***

58.8  ±  16.5*##

< 0.001

BMI (kg/m2)

25.8  ±  4.8

17.9  ±  4.2***

21.6  ±  4.8**#

< 0.001

Weight loss (%)

1.26  ± 5.10

13.8  ±  5.7***

17.1  ±  8.6***

< 0.001

Triceps Skinfold Thickness (mm)

19.3 ±  6.8

13.9 ±  6.2

14.3 ± 6.6*

0.009

Mid-upper arm circumference (cm)

28.7  ±  4.1

23.7  ±  3.5**

24.8  ±  4.3**

< 0.001

Arm Muscle Perimeter (cm)

22.6  ±  3.2

19.4 ±  2.9*

19.9  ±  3.3**

0.002

Albumin (g/dl)

4.22 ±  0.25

4.26  ±  0.43

3.62  ±  0.61***###

< 0.001

Prealbumin (mg/dl)

25.2 ±  4.6

24.9 ±  4.8

18.8 ± 6.8***##

< 0.001

Transferrin (mg/dl)

271.1 ±  54.5

231.8 ±  48.5

208.4 ±  66.8***

< 0.001

RBP (mg/dl)

3.65 ±  0.86

4.01 ±  0.82

2.95 ± 0.87*#

0.004

C3 (mg/dl)

104.5 ±  16.5

114.0 ±  23.4

113.8 ± 25.7

0.223

Total cholesterol (mg/dl)

193.2 ±  42.3

195.5 ±  43.8

172.3 ±  48.9

0.154

Triglycerides (mg/dl)

93.0 (67.8, 143.3)

92.0 (53.3, 115.5)

91.0 (79.0, 122.0)

0.308

Lymphocytes (× 109/l)

1.94 ± 0.61

1.92 ± 0.77

1.55 ± 0.80

0.152

  1. Data are expressed as mean ± SD or median and 25th and 75th percentiles for parametric and non-parametric data, respectively. One-way analysis of variance of parametric data or Kruskal Wallis test for non-parametric data were employed to compare groups, followed by a post hoc test (Student-Newman-Keuls or Dunn’s Multiple Comparison test, respectively). * p < 0.05, **p < 0.01 and ***p < 0.001 vs NN; # p < 0.05 vs DRM-I; ##p < 0.01 vs DRM-I; ###p < 0.001 vs DRM-I
  2. DRM-I Disease-related malnutrition without inflammation, DRM + I Disease-related malnutrition with inflammation, NN Normonutrition