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Table 1 Anthropometric, clinic and metabolic parameters in well nourished and disease-related malnutrition subjects according to the presence of inflammation

From: Malnutrition impairs mitochondrial function and leukocyte activation

 NN
(n = 34)
DRM-I
(n = 21)
DRM + I
(n = 28)
p value
Age (years)60.0  ±  16.251.1 ±  23.565.8 ±  13.4#0.030
Gender (% men)23.514.357.10.002
Weight (Kg)67.9  ±  15.645.8 ±  10.3***58.8  ±  16.5*##< 0.001
BMI (kg/m2)25.8  ±  4.817.9  ±  4.2***21.6  ±  4.8**#< 0.001
Weight loss (%)1.26  ± 5.1013.8  ±  5.7***17.1  ±  8.6***< 0.001
Triceps Skinfold Thickness (mm)19.3 ±  6.813.9 ±  6.214.3 ± 6.6*0.009
Mid-upper arm circumference (cm)28.7  ±  4.123.7  ±  3.5**24.8  ±  4.3**< 0.001
Arm Muscle Perimeter (cm)22.6  ±  3.219.4 ±  2.9*19.9  ±  3.3**0.002
Albumin (g/dl)4.22 ±  0.254.26  ±  0.433.62  ±  0.61***###< 0.001
Prealbumin (mg/dl)25.2 ±  4.624.9 ±  4.818.8 ± 6.8***##< 0.001
Transferrin (mg/dl)271.1 ±  54.5231.8 ±  48.5208.4 ±  66.8***< 0.001
RBP (mg/dl)3.65 ±  0.864.01 ±  0.822.95 ± 0.87*#0.004
C3 (mg/dl)104.5 ±  16.5114.0 ±  23.4113.8 ± 25.70.223
Total cholesterol (mg/dl)193.2 ±  42.3195.5 ±  43.8172.3 ±  48.90.154
Triglycerides (mg/dl)93.0 (67.8, 143.3)92.0 (53.3, 115.5)91.0 (79.0, 122.0)0.308
Lymphocytes (× 109/l)1.94 ± 0.611.92 ± 0.771.55 ± 0.800.152
  1. Data are expressed as mean ± SD or median and 25th and 75th percentiles for parametric and non-parametric data, respectively. One-way analysis of variance of parametric data or Kruskal Wallis test for non-parametric data were employed to compare groups, followed by a post hoc test (Student-Newman-Keuls or Dunn’s Multiple Comparison test, respectively). * p < 0.05, **p < 0.01 and ***p < 0.001 vs NN; # p < 0.05 vs DRM-I; ##p < 0.01 vs DRM-I; ###p < 0.001 vs DRM-I
  2. DRM-I Disease-related malnutrition without inflammation, DRM + I Disease-related malnutrition with inflammation, NN Normonutrition