Dietary TAC (mmol/day) | Â | M1 | M2 | M3 | |||
---|---|---|---|---|---|---|---|
N (%) cases | HR [95% CI] | p-trend | HR [95% CI] | p-trend | HR [95% CI] | p-trend | |
Coffee | Â | Â | 0.02 | Â | 0.03 | Â | 0.14 |
 Q1 (< 2.46) | 1820 (19.47) | Reference |  | Reference |  | Reference |  |
 Q2 (2.46–9.15) | 1861 (19.90) | 0.99 [0.93; 1.06] | 1.01 [0.94; 1.08] | 0.98 [0.91; 1.05] | |||
 Q3 (9.15–15.97) | 1896 (20.28) | 1.06 [0.99; 1.14] | 1.07 [1.00; 1.14] | 1.00 [0.93; 1.08] | |||
 Q4 (15.97–24.99) | 1925 (20.59) | 1.08 [1.01; 1.16] | 1.09 [1.01; 1.16] | 0.99 [0.91; 1.09] | |||
 Q5 (>  24.99) | 1848 (19.76) | 1.07 [0.99; 1.14] |  | 1.07 [0.99; 1.15] |  | 0.91 [0.80; 1.04] |  |
Tea | Â | Â | 0.02 | Â | 0.12 | Â | 0.73 |
 Q1 (0) | 3814 (40.79) | Reference |  | Reference |  | Reference |  |
 Q2 (0.01–0.36) | 1412 (15.10) | 0.95 [0.89; 1.02] | 0.95 [0.89; 1.02] | 0.97 [0.91; 1.03] | |||
 Q3 (0.36–1.25) | 1411 (15.09) | 0.97 [0.91; 1.01] | 0.97 [0.91; 1.03] | 0.98 [0.92; 1.05] | |||
 Q4 (1.25–2.22) | 1385 (14.81) | 0.97 [0.91; 1.03] | 0.99 [0.92; 1.05] | 1.01 [0.94; 1.08] | |||
 Q5 (>  2.22) | 1328 (14.20) | 0.93 [0.87; 0.99] |  | 0.95 [0.87; 1.01] |  | 0.97 [0.91; 1.04] |  |
Chocolate | Â | Â | 0.18 | Â | 0. 11 | Â | 0.23 |
 Q1 (0) | 4175 (47.30) | Reference |  | Reference |  | Reference |  |
 Q2 (0.02–0.25) | 1285 (14.56) | 0.98 [0.92; 1.04] | 0.96 [0.90; 1.02] | 0.99 [0.90; 1.02] | |||
 Q3 (0.26–0.53) | 920 (10.42) | 0.91 [0.85; 0.98] | 0.90 [0.84; 0.97] | 0.91 [0.85; 0.98] | |||
 Q4 (0.54–1.30) | 1151 (13.04) | 0.96 [0.90; 1.03] | 0.96 [0.89; 1.02] | 0.96 [0.90; 1.03] | |||
 Q5 (>  1.4) | 1295 (14.67) | 0.95 [0.89; 1.02] |  | 0.94 [0.88; 1.00] |  | 0.95 [0.89; 1.02] |  |
Fruit and vegetables |  |  | 0.001 |  | 0. 0003 |  | < 0.0001 |
 Q1 (<  0.99) | 1907 (20.40) | Reference |  | Reference |  | Reference |  |
 Q2 (0.99–1.36) | 1836 (19.64) | 0.92 [0.86; 0.98] | 0.91 [0.85; 0.98] | 0.91 [0.85; 0.98] | |||
 Q3 (1.36–1.71) | 1869 (19.99) | 0.92 [0.86; 0.99] | 0.92 [0.86; 0.98] | 0.91 [0.85; 0.97] | |||
 Q4 (1.71–2.21) | 1815 (19.41) | 0.89 [0.83; 0.95] | 0.87 [0.82; 0.93] | 0.86 [0.80; 0.92] | |||
 Q5 (>  2.21) | 1923 (20.57) | 0.88 [0.83; 0.95] |  | 0.87 [0.82; 0.94] |  | 0.84 [0.78; 0.91] |  |
Wine | Â | Â | 0.85 | Â | 0.84 | Â | 0.008 |
 Q1 (0) | 2202 (23.55) | Reference |  | Reference |  | Reference |  |
 Q2 (0.01–0.23) | 1600 (17.11) | 0.97 [0.90; 1.03] | 0.96 [0.90; 1.03] | 0.95 [0.89; 1.02] | |||
 Q3 (0.23–0.71) | 1805 (19.30) | 0.95 [0.89; 1.02] | 0.95 [0.89; 1.01] | 0.92 [0.86; 0.99] | |||
 Q4 (0.71–1.68) | 1840 (19.68) | 0.93 [0.87; 0.99] | 0.93 [0.87; 0.99] | 0.88 [0.82; 0.95] | |||
 Q5 (>  1.68) | 1903 (20.35) | 0.97 [0.91; 1.04] |  | 0.98 [0.92; 1.05] |  | 0.86 [0.77; 0.95] |  |
Other sources | Â | Â | 0.002 | Â | 0.006 | Â | 0.01 |
 Q1 (<  0.46) | 1994 (21.33) | Reference |  | Reference |  | Reference |  |
 Q2 (0.46–0.63) | 1913 (20.46) | 0.96 [0.89; 1.02] | 0.95 [0.89; 1.02] | 0.96 [0.90; 1.03] | |||
 Q3 (0.63–0.82) | 1848 (19.76) | 0.93 [0.87; 0.99] | 0.94 [0.88; 1.01] | 0.96 [0.89; 1.03] | |||
 Q4 (0.82–1.09) | 1748 (18.70) | 0.86 [0.80; 0.92] | 0.86 [0.80; 0.93] | 0.89 [0.82; 0.95] | |||
 Q5 (>  1.09) | 1847 (19.75) | 0.91 [0.85; 0.99] |  | 0.92 [0.86; 1.00] |  | 0.93 [0.86; 1.01] |  |