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Table 3 Mutually adjusted analysis. Hazard ratios of hypertension according to dietary total antioxidant capacity intake in women, partitioned into TAC from coffee and TAC from all other sources. (N = 40,576). E3N Cohort, France 1993–2008

From: High dietary total antioxidant capacity is associated with a reduced risk of hypertension in French women

Dietary TAC (mmol/day)   M1 M2 M3
N (%) cases HR [95% CI] p-trend HR [95% CI] p-trend HR [95% CI] p-trend
non-coffee TAC
 Q1 (< 2.95) 1948 (20.8) Reference 0.001 Reference 0.006 Reference < 0.0001
 Q2 (2.95–3.99) 1909 (20.4) 0.95 [0.89; 1.01]   0.94 [0.88; 1.00]   0.93 [0.87; 0.99]  
 Q3 (3.99–5.52) 1831 (19.6) 0.89 [0.84; 0.96]   0.90 [0.84; 0.96]   0.88 [0.82; 0.94]  
 Q4 (5.52–6.69) 1845 (19.7) 0.91 [0.85; 0.97]   0.91 [0.85; 0.97]   0.88 [0.82; 0.94]  
 Q5 (> 6.96) 1817 (19.4) 0.90 [0.90; 0.83]   0.90 [0.84; 0.97]   0.85 [0.79; 0.92]  
Coffee TAC
 Q1 (< 2.46) 1820 (19.5) Reference 0.01 Reference 0.70 Reference 0.03
 Q2 (2.46–9.15) 1861 (19.9) 1.00 [093; 1.06]   1.00 [0.93; 1.06]   0.97 [0.90; 1.03]  
 Q3 (9.15–15.97) 1898 (20.3) 1.05 [0.98; 1.11]   1.02 [0.96; 1.09]   0.96 [0.89; 1.03]  
 Q4 (15.97–24.99) 1923 (20.6) 1.07 [1.00; 1.15]   1.04 [0.98; 1.11]   0.95 [0.87; 1.03]  
 Q5 (>  24.99) 1848 (19.8) 1.06 [1.00; 1.14]   1.00 [0.94; 1.07]   0.86 [0.75; 0.97]  
  1. M1: Age as the time scale + energy without alcohol
  2. M2: M1 + (Diabetes, treated hypercholesterolemia, education, family history of hypertension, smoking, physical activity, body mass index)
  3. M3: M2 + Na (mg), K (mg), Mg (mg), AGPIw3 (mg), alcohol (g)