Association of kidney function-related dietary pattern, weight status, and cardiovascular risk factors with severity of impaired kidney function in middle-aged and older adults with chronic kidney disease: a cross-sectional population study

Table 4 The association of dietary pattern scores with weight status, cardiovascular risk factors, and the severity of impaired kidney function (n = 41,128)^a

	Dietary pattern scores
	Tertile 1 (Ref)	Tertile 2^b		Tertile 3^c
	Tertile 1 (Ref)	OR (95% CI)	P	OR (95% CI)	P
Weight status
BMI
Overweight	1.00	1.13 (1.06–1.21)	< 0.001	1.36 (1.27–1.46)	< 0.001
Obese	1.00	1.43 (1.31–1.57)	< 0.001	2.07 (1.89–2.27)	< 0.001
High waist circumference	1.00	1.28 (1.19–1.38)	< 0.001	1.72 (1.60–1.85)	< 0.001
High WHR	1.00	1.24 (1.16–1.32)	< 0.001	1.70 (1.59–1.82)	< 0.001
High body fat mass	1.00	1.24 (1.17–1.33)	< 0.001	1.58 (1.48–1.68)	< 0.001
Cardiovascular risk factors
Hypertension	1.00	1.02 (0.95–1.10)	0.62	1.04 (0.96–1.12)	0.31
Diabetes	1.00	1.12 (1.00–1.24)	0.047	1.15 (1.03–1.28)	0.014
High TG	1.00	1.13 (1.03–1.24)	0.012	1.24 (1.13–1.37)	< 0.001
High TC	1.00	1.03 (0.95–1.11)	0.47	1.23 (1.14–1.33)	< 0.001
Low HDL-C	1.00	1.05 (0.92–1.20)	0.49	1.00 (0.88–1.15)	0.96
High LDL-C	1.00	1.01 (0.93–1.10)	0.78	1.17 (1.08–1.28)	< 0.001
High TC/HDL-C	1.00	1.14 (1.01–1.28)	0.032	1.31 (1.17–1.47)	< 0.001
Hypercalcemia	1.00	1.05 (0.98–1.12)	0.29	1.10 (1.02–1.17)	0.003
High phosphorus (≥ 1.2 mmol/L)	1.00	0.98 (0.92–1.04)	0.51	1.00 (0.94–1.07)	0.98
Severity of kidney function
Moderately/severely impaired	1.00	1.12 (1.00–1.25)	0.049	1.15 (1.02–1.29)	0.019

BMI body mass index, WHR waist-to-hip ratio, TG triglycerides, TC total cholesterol, HDL-C high density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, TC/HDL-C total cholesterol-to-HDL-C ratio
^aAdjusted for model 2. Weight status category was adjusted for age, gender, smoking status, drinking status, physical activity, high cardiovascular risk profile, hypertension status, diabetes status, albumin, and CRP. Cardiovascular risk factors and the severity of kidney function categories were adjusted for age, gender, BMI, smoking status, drinking status, physical activity, high cardiovascular risk profile, hypertension status (except hypertension variable), diabetes status (except diabetes variable), albumin, and CRP. Tertile 1 (dietary pattern score: −1.34-1.22, n = 13,769) was used for the reference
^bTertile 2 (dietary pattern scores: 1.23–1.89, n = 13,656)
^cTertile 3 (dietary pattern scores: 1.90–6.55, n = 13,703)

ISSN: 1475-2891