Association of kidney function-related dietary pattern, weight status, and cardiovascular risk factors with severity of impaired kidney function in middle-aged and older adults with chronic kidney disease: a cross-sectional population study

Table 2 Multivariable logistic regression of weight status and cardiovascular risk factors for moderately/severely impaired kidney function

	Model 1^a		Model 2^b
	OR (95% CI)	P	OR (95% CI)	P
Weight status
BMI, ref.: normal
Overweight (n = 12,407)	1.32 (1.21–1.44)	< 0.001	1.25 (1.12–1.39)	< 0.001
Obese (n = 6852)	1.58 (1.43–1.75)	< 0.001	1.28 (1.12–1.45)	< 0.001
High waist circumference (n = 10,187)	1.29 (1.19–1.40)	< 0.001	1.10 (0.99–1.22)	0.052
High WHR (n = 15,673)	1.27 (1.17–1.37)	< 0.001	1.11 (1.00–1.23)	0.039
High body fat mass (n = 15,215)	1.24 (1.15–1.35)	< 0.001	1.06 (0.97–1.17)	0.219
Cardiovascular risk factors
Hypertension (n = 11,779)	1.57 (1.44–1.70)	< 0.001	1.43 (1.29–1.58)	< 0.001
Diabetes (n = 3974)	1.48 (1.34–1.63)	< 0.001	1.30 (1.15–1.48)	< 0.001
High TG (n = 5627)	1.51 (1.36–1.67)	< 0.001	1.44 (1.27–1.63)	< 0.001
High TC (n = 7510)	1.44 (1.32–1.58)	< 0.001	1.39 (1.25–1.55)	< 0.001
Low HDL-C (n = 2335)	1.41 (1.22–1.64)	< 0.001	1.40 (1.18–1.67)	< 0.001
High LDL-C (n = 5709)	1.40 (1.27–1.54)	< 0.001	1.30 (1.16–1.46)	< 0.001
High TC/HDL-C (n = 3527)	1.62 (1.44–1.84)	< 0.001	1.52 (1.31–1.77)	< 0.001
Hypercalcemia (n = 12,589)	1.52 (1.40–1.65)	< 0.001	1.56 (1.41–1.72)	< 0.001
High phosphorus (n = 420)	1.10 (1.01–1.20)	0.037	1.11 (1.00–1.23)	0.046

BMI body mass index, WHR waist-to-hip ratio, TG triglycerides, TC total cholesterol, HDL-C high density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, TC/HDL-C total cholesterol-to-HDL-C ratio
^aModel 1 was adjusted for age and gender (for weight status category). For cardiovascular risk factors category, model 1 was adjusted for age, gender, and BMI
^bModel 2 was adjusted for age, gender, smoking status, drinking status, physical activity, high cardiovascular risk profile, hypertension status, diabetes status, albumin, and CRP (for weight status category). For cardiovascular risk factor category, model 2 was adjusted for age, gender, BMI, smoking status, drinking status, physical activity, high cardiovascular risk profile, hypertension status (except hypertension variable), diabetes status (except diabetes variable), albumin, and CRP

ISSN: 1475-2891