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Table 2 The numbers, mortality and significance of differences by criterion for studies analysed

From: Severely malnourished children with a low weight-for-height have similar mortality to those with a low mid-upper-arm-circumference: II. Systematic literature review and meta-analysis

Ref Study Author & year Kwash Total SAM S-whz S-muac S-both S-whz S-muac S-both WHZ v MUAC
    Total dead Total dead Total dead Total dead Total dead CFR CFR CFR χ2 χ2 Fisher Cramer
# #   # # # # # # # # # # % % % value p (2-tail) p (1-tail) V
Studies giving numbers of children fulfilling both WHZ and MUAC criteria
 41 1 Aguayo 2015 231 11 6076 32 1333 3 859 2 3884 27 0.23 0.23 0.70    0.65 0.00
 42 2 Grellety 2012 2 0 530 13 177 3 167 2 186 8 1.69 1.20 4.30    0.53 0.02
 21 3 Grellety 2015 excl excl 2205 40 1486 13 21 1 698 26 0.87 4.76 3.72    0.22 0.12
 43 4 Isanaka 2015 excl excl 2399 13 530 3 929 4 940 6 0.57 0.43 0.64    0.48 0.03
 44 5 Lowlaavar 2016 excl excl 262 21 171 11 32 0 59 10 6.43 0.00 16.95    0.14 0.10
 45 6 LaCourse 2014 97 8 210 15 29 2 68 4 16 1 6.90 5.88 6.25    0.58 0.02
 35 7 Olofin 2016 ng ng 767 145 116 18 483 64 168 63 15.50 13.25 37.50 0.41 0.52 0.31 0.03
Studies including oedema
 46 8 Berkley 2005 390 ng 1140 193 267 27 384 42 489 124 10.11 10.94 25.36 0.11 0.74 0.42 0.01
 47 9 Chiabi 2017 ng ng 106 22 23 1 21 3 62 18 4.35 14.29 29.03    0.27 0.17
 48 10 Sachdeva 2016 ng ng 447 59 228 18 75 15 144 26 7.89 20.00 18.06 8.52 0.004 0.004 0.17
Studies where children fulfilling both criteria are incorporated into both the WHZ and MUAC categories
        All-whz All-muac    All-whz All-muac   All-whz v All-muac
 49 11 Burza 2016 ng ng 650 36 295 26 650 36    8.81 5.54   3.55 0.06 0.042 0.06
 50 12 Mogeni 2011 392 ng 1768 217 966 101 802 116    10.46 14.46   6.54 0.011   0.06
 51 13 Sylla 2015 ng ng 272 42 90 27 117 15    30.00 12.82   9.28 0.002 0.002 0.21
 52 14 Vella 1990 ng ng 118 22 34 3 96 18    8.82 18.75     0.14 0.12
 53 15 Dramaix 1993 320 102 442 122 267 63 175 57    23.60 32.57   4.31 0.038 0.025 0.10
 54 16 Girum 2017 363 25 545 51 130 26 277 41    20.00 14.80   1.74 0.19 0.12 0.07
 55 17 Savadogo 2007 excl excl 1322 212 930 168 387 95    18.03 24.50   7.19 0.007   0.01
 36 18 Garenne1987 ng ng 622 63 92 14 569 54    15.22 9.49   2.81 0.09 0.06 0.07
 37 19 Garenne 2009 ng ng 281 44 183 23 98 21    12.57 21.43   3.79 0.051 0.040 0.12
 37 20 Garenne 2009 ng ng 388 25 150 9 238 16    6.00 6.72   0.08 0.78 0.48 0.01
 38 21 Broeck 1993 56 8 652 13 113 3 539 6    2.65 1.11     0.14 0.05
  1. S-whz WHZ below cut off point with MUAC above cut-off point as defined in the paper, S-muac MUAC below cut off point with WHZ above cut-off point as defined in the paper, S-both MUAC and WHZ both below the cut-off point as defined in the paper, All-whz WHZ below the cut-off point, with MUAC either above or below the cut-off point as defined in the paper, All-muac MUAC below the cut-off point, WHZ either above or below the cut-off as defined in the paper, excl excluded from analysis, ng not given in report, CFR Case Fatality Rate in percentage, χ2 Pearson’s chi squared test (two-way significance), Fisher Fisher’s exact test (one-tailed test of significance), Cramer Cramer’s V test of association between the groups. The higher CFR and significant differences are shown in bold script