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Table 2 Dietary patterns and Colorectal Cancer Survival (Multivariable adjusted analysis); Newfoundland and Labrador Familial Colorectal Cancer Cohort (1999–2003)

From: Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort

Dietary Pattern Identified by

Combined Mortality, Recurrence and Metastasis

Overall Mortality

HRa (95% CI)

P-trend

HR (95% CI)

p-trend

Factor Analysis

Processed Meat patterna

1.82 (1.07–3.09)*

0.09

1.53 (0.85–2.27)

0.25

Prudent Vegetable Patterna

1.12 (0.69–1.84)

0.62

1.03 (0.61–1.75)

0.90

High-sugar Patterna

1.02 (0.62–1.69)

0.89

1.27 (0.72–2.23)

0.62

Cluster Analysis

Fruit and Veg, Whole Grain, Fish, wine (Cluster I)

1c

 

1c

 

Meat, dairy products(Cluster II),

2.19 (1.03–4.67)*

 

2.04 (0.96–4.35)

 

Refined grains, sugar soft Drinks (Cluster III)

1.95 (1.13–3.37)*

 

2.05 (1.18–3.57)*

 

Many foods (Cluster IV)

1.55 (0.92–2.61)

 

1.50 (0.9–2.56)

 

Index Based

DIIa

0.89 (0.56–1.42)

0.46

0.78 (0.47–1.25)

0.33

Alt. Mediterranean Diet Scoreb

1.44 (0.92–2.25)

0.08

1.62 (1.04–2.56)*

0.03

Recommended Food Scoreb

1.51(0.92–2.48)

0.06

1.54 (0.92–2.56)

0.045

  1. aHazards Ratio while comparing with highest quartile to the lowest (reference quartile)
  2. bHazards Ratio while comparing with lowest quartile to highest (reference quartile)
  3. cReference group
  4. *Statistically significant
  5. HR ratios Adjusted for energy, stage of cancer, sex, age, marital status, tumour location, screening history, intake of alcohol, radiation and chemo therapy status, Microsatellite instability status wherever applicable
  6. Events are defined as all-cause deaths for overall Mortality and death/recurrence/metastasis (which occurred earliest) for cMRM