Table 1 Characteristics of study participants with their overall survival status (Univariate); Newfoundland and Labrador Familial Colorectal Cancer Cohort (1999–2003)
Characteristic | No. of patientsa | No. of deaths (%) | P log-rank |
|---|---|---|---|
Age at diagnosis | |||
  ≤ 60 | 231 | 62 (26.83) |  |
  > 60 | 301 | 108 (35.88) | 0.04 |
Sex | |||
 Female | 211 | 57 (27.02) |  |
 Male | 321 | 113 (35.20) | 0.02 |
Family history | |||
 Yes | 16 | 6 (37.5) |  |
 No | 516 | 164 (31.78) | 0.61 |
Reported screening procedure | |||
 Yes | 68 | 15 (22.05) |  |
 No | 464 | 155 (33.4) | 0.08 |
Stage at diagnosis | |||
 I/II | 311 | 74 (23.79) |  |
 III/IV | 221 | 96 (43.43) | < 0.001 |
Diabetes History | |||
 Yes | 115 | 42 (36.52) | 0.22 |
 No | 417 | 128 (30.69) | |
History of High Cholesterol | |||
 Yes | 153 | 44 (28.75) |  |
 No | 349 | 117 (33.52) | 0.44 |
Tumour location | |||
 Colon | 349 | 105 (30.09) |  |
 Rectum | 183 | 65 (35.51) | 0.25 |
Smoke | |||
 No | 139 | 34 (24.44) | 0.07 |
 Yes | 393 | 136 (34.60) | |
Physical Activity (Met-hrs/week) | |||
 Low (< 10) | 175 | 52 (29.71) |  |
 Median (10–50) | 163 | 56 (34.35) | 0.27 |
 High (50+) | 193 | 62 (32.12) |  |
MSI status | |||
 MSI-L | 440 | 154 (35.0) |  |
 MSI-H | 61 | 6 (9.83) | < 0.002 |
Reported chemo Therapy | |||
 Yes | 108 | 42 (38.88) |  |
 No | 421 | 128 (30.40) | 0.06 |