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Table 2 Change after 16 weeks in metabolic, anthropometric and dietary intake parameters in response to three different methods of nutrition therapy

From: Effects of nutrition therapy on HbA1c and cardiovascular disease risk factors in overweight and obese patients with type 2 diabetes

 

Group A (n = 36)

Group B (n = 36)

Group C (n = 36)

P value

HbA1c (%)

0.06 (−0.28 to 0.41)

− 0.66 (− 1.03 to − 0.30)***

−0.61 (− 1.0 to − 0.23)**

< 0.001

Fasting plasma glucose (mmol/L)

− 0.5 (− 1.5 to 0.6)

− 0.9 (− 2.0 to 0.2)

−0.7 (− 1.8 to 0.4)

0.09

Fasting insulin (pmol/L)

− 12 (− 37 to 12)

− 18 (− 6 to 1)

− 5 (−9 to − 1)*

0.76

HOMA-IR

− 2.1 (− 4.4 to 0.3)

− 1.9 (− 4.3 to 0.5)

− 2.8 (− 5.2 to − 0.3)*

0.51

Total cholesterol (mmol/L)

−0.07 (− 0.29 to 0.16)

0.06 (− 0.18 to 0.30)

0.11 (− 0.14 to 0.37)

0.50

HDL-cholesterol (mmol/L)

0.02 (− 0.03 to 0.07)

0.02 (− 0.04 to 0.08)

0.07 (0.01 to 0.13)*

0.28

LDL-cholesterol (mmol/L)

−0.06 (− 0.25 to 0.13)

0.05 (− 0.16 to 0.26)

0.10 (− 0.12 to 0.33)

0.71

Triglycerides (mmol/L)

− 0.05 (− 0.27 to 0.17)

−0.18 (− 0.41 to 0.06)

−0.09 (− 0.33 to 0.16)

0.31

Albumin/creatinine ratio (mg/mmol)

0.50 (− 1.92 to 2.92)

− 0.23 (− 2.72 to 2.27)

− 0.51 (− 3.08 to 2.07)

0.63

hsCRP (nmol/L)

9.2 (− 30.0 to 48.3)

14.4 (− 27.8 to 56.5)

− 6.2 (− 50.6 to 38.9)

0.81

Body weight (kg)

−1.11 (− 2.46 to 0.23)

− 3.49 (− 4.93 to − 2.05)***

− 2.93 (− 4.45 to − 1.42)***

0.11

BMI (kg/m2)

−0.43 (− 0.92 to 0.06)

−1.26 (− 1.78 to − 0.74)***

−1.06 (− 1.61 to − 0.52)***

0.13

Body fat (%)

−0.1 (− 0.9 to 0.6)

−1.6 (− 2.4 to − 0.8)***

−1.2 (− 2.0 to − 0.3)**

< 0.05

Visceral fat (arbitrary units)

0.01 (− 1.0 to 0.9)

−1.2 (− 2.2 to − 0.2)*

−0.3 (− 1.3 to 0.8)

0.40

Waist circumference (cm)

−0.4 (−2.3 to 1.5)

− 5.0 (− 7.0 to − 2.9)***

−2.9 (− 5.0 to − 0.8)**

< 0.01

Hip circumference (cm)

−1.8 (− 3.6 to − 0.1)*

−3.6 (− 5.2 to − 1.7)***

− 2.9 (− 4.8 to − 1.0)**

0.37

Wait/Hip ratio

0.01 (−0.01 to 0.03)

− 0.01 (− 0.03 to 0.01)

0.00 (− 0.02 to 0.02)

0.14

Systolic blood pressure (mmHg)

3 (− 2 to 8)

7 (2 to 13)***

0 (−6 to 6)

< 0.05

Diastolic blood pressure (mmHg)

3 (0 to 7)

1 (− 3 to 5)

3 (−2 to7)

0.41

Daily energy intake (kcal)

− 206 (− 394 to − 18)*

− 269 (− 469 to − 69)**

− 382 (− 586 to − 177)***

0.40

Carbohydrate intake (g)

−33.4 (− 60.4 to − 6.3)*

−29.7 (− 58.6 to − 0.9)*

−50.3 (− 79.7 to − 20.9)**

0.62

 % Energy from carbohydrates

−1.4 (− 4.2 to 1.4)

− 0.5 (− 3.5 to 2.6)

−2.9 (− 6.0 to 0.3)

0.50

Total fat intake (g)

− 9.9 (− 19.8 to − 0.01)*

− 18.6 (− 29.2 to − 8.0)***

−16.9 (− 27.7 to − 6.1)**

0.16

 % Energy from total fat

−0.2 (− 3.0 to 2.5)

−4.2 (− 7.2 to − 1.2)**

−1.2 (− 4.3 to 1.9)

0.10

Saturated fat intake (g)

−4.3 (− 7.7 to − 0.9)*

−10.1 (− 13.7 to − 6.4)***

−9.3 (− 13.1 to − 5.6)***

< 0.05

 % Energy from saturated fat

−0.9 (− 2.1 to 0.3)

−3.3 (− 4.6 to − 2.1)***

−2.7 (− 4.0 to − 1.3)***

< 0.01

Protein intake (g)

1.3 (− 6.9 to 9.5)

11.0 (2.1 to 19.9)*

0.4 (− 8.8 to 9.7)

0.29

 % Energy from protein

1.6 (− 0.3 to 3.5)

4.8 (2.8 to 6.8)***

4.2 (2.1 to 6.2)***

< 0.001

Fiber intake (g)

1.6 (− 0.5 to 3.8)

4.0 (1.6 to 6.4)**

2.7 (0.2 to 5.2)*

0.58

  1. Values are mean (95% CI). hsCRP high-sensitivity C-reactive protein. *p < 0.05, **p < 0.01, ***p < 0.001 compared to baseline. p value for group*time effect. Group A: individualized nutrition therapy, Group B: Structured nutrition therapy, Group C: Structured nutrition therapy + weekly phone support