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Table 3 Odds ratios (OR) and 95% confidence intervals (Cl) for colorectal cancer sub-site in relation to nut consumption

From: The relationship between nut intake and risk of colorectal cancer: a case control study

  Control   Colorectal cancer   Proximal colon   Distal colon   Rectum
Consumption frequency No No Crude OR (95% CI) Multivariate OR (95% CI)* No Crude OR (95% CI) Multivariate OR (95% CI)* No Crude OR (95% CI) Multivariate OR (95% CI)* No Crude OR (95% CI) Multivariate OR (95% CI)*
All 1846 923    166    291    444   
 None 585 377 1.00 1.00 66 1.00 1.00 124 1.00 1.00 179 1.00 1.00
  < 1 serving per week 832 436 0.81 (0.68–0.97) 0.91 (0.74–1.12) 73 0.78 (0.55–1.10) 0.67 (0.60–1.25) 135 0.77 (0.59–1.00) 0.85 (0.64–1.14) 218 0.86 (0.68–1.07) 0.96 (0.74–1.24)
 1–3 servings per week 185 63 0.53 (0.39–0.72) 0.62 (0.43–0.91) 18 0.86 (0.50–1.49) 0.97 (0.54–1.77) 17 0.43 (0.25–0.74) 0.49 (0.28–0.88) 25 0.44 (0.28–0.69) 0.51 (0.31–0.85)
  ≥ 3 servings per week 224 47 0.30 (0.21–0.42) 0.30 (0.20–0.45) 9 0.33 (0.16–0.67) 0.32 (0.15–0.69) 15 0.29 (0.17–0.51) 0.29 (0.16–0.53) 22 0.30 (0.19–0.47) 0.30 (0.18–0.50)
P for trend    < 0.001 < 0.001   0.003 0.011   < 0.001 < 0.001   < 0.001 < 0.001
Men 1250 625    113    178    320   
 None 426 256 1.00 1.00 44 1.00 1.00 79 1.00 1.00 127 1.00 1.00
  < 1 serving per week 564 291 0.86 (0.70–1.06) 0.90 (0.70–1.16) 49 0.84 (0.55–1.29) 0.85 (0.55–1.34) 77 0.74 (0.53–1.03) 0.77 (0.54–1.11) 160 0.95 (0.73–1.24) 1.00 (0.74–1.36)
 1–3 servings per week 116 47 0.67 (0.46–0.98) 0.78 (0.50–1.23) 15 1.25 (0.67–2.33) 1.27 (0.65–2.51) 10 0.47 (0.23–0.93) 0.54 (0.26–1.14) 20 0.58 (0.35–0.97) 0.66 (0.37–1.19)
  ≥ 3 servings per week 144 31 0.36 (0.24–0.54) 0.28 (0.17–0.47) 5 0.34 (0.13–0.86) 0.25 (0.09–0.70) 12 0.45 (0.24–0.85) 0.39 (0.19–0.80) 13 0.30 (0.16–0.55) 0.23 (0.12–0.46)
P for trend    < 0.001 < 0.001   0.098 0.050   0.001 0.004   < 0.001 < 0.001
Women 596 298    53    113    124   
 None 159 121 1.00 1.00 22 1.00 1.00 45 1.00 1.00 52 1.00 1.00
  < 1 serving per week 268 145 0.71 (0.52–0.97) 0.94 (0.65–1.38) 24 0.65 (0.35–1.19) 0.99 (0.50–1.94) 58 0.77 (0.49–1.18) 0.99 (0.61–1.63) 58 0.66 (0.43–1.01) 0.87 (0.54–1.40)
 1–3 servings per week 69 16 0.31 (0.17–0.55) 0.37 (0.18–0.77) 3 0.31 (0.09–1.09) 0.51 (0.13–2.00) 7 0.36 (0.15–0.83) 0.39 (0.15–1.03) 5 0.22 (0.09–0.58) 0.26 (0.10–0.76)
  ≥ 3 servings per week 100 16 0.21 (0.12–0.38) 0.30 (0.15–0.60) 4 0.29 (0.10–0.86) 0.54 (0.17–1.83) 3 0.11 (0.03–0.35) 0.13 (0.04–0.48) 9 0.28 (0.13–0.58) 0.40 (0.17–0.95)
P for trend    < 0.001 < 0.001   0.007 0.222   < 0.001 < 0.001   < 0.001 0.006
  1. Adjusted for age(< 50 years, 50–59, 60 or older), education(less than high school, high school, college or above, and missing) alcohol consumption(non-drinker, ex-drinker, current drinker, and missing), regular exercise(no, yes, and missing), body mass index(< 25 kg/m2, ≥25 kg/m2, and missing), red meat(continuous), fruit and vegetable intake (continuous), calcium(continuous), vitamin D(continuous), and total energy intake(continuous)