Effect of weight loss on circulating fatty acid profiles in overweight subjects with high visceral fat area: a 12-week randomized controlled trial

Table 2 CT and DEXA evaluation of the weight-maintenance (control) and weight-loss groups at baseline and 12-week follow-up

	Weight-maintenance group (n = 38)			Weight-loss group (n = 37)			P ^a	P ^b	P ^c	P ^d
	Baseline		Follow-up	Baseline		Follow-up	P ^a	P ^b	P ^c	P ^d
Percent weight change		0.63 ± 0.15			− 3.44 ± 0.34		< 0.001
CT evaluation (L4)
Whole fat area (cm²)	327.0 ± 6.32		333.3 ± 6.23	319.8 ± 6.65		298.5 ± 7.23^***	0.435	< 0.001
Change		6.34 ± 4.72			− 21.3 ± 4.70				< 0.001	< 0.001
Visceral fat area (cm²)	118.2 ± 2.34		121.9 ± 3.26	118.3 ± 3.14		100.6 ± 3.67^***	0.989	< 0.001
Change		3.65 ± 2.31			− 17.7 ± 3.30				< 0.001	< 0.001
Subcutaneous fat area (cm²)	208.7 ± 6.98		211.4 ± 6.24	201.5 ± 7.06		197.8 ± 6.90	0.468	0.148
Change		2.69 ± 4.17			− 3.66 ± 2.54				0.200	0.099
Visceral/subcutaneous fat ratio (%)	0.60 ± 0.03		0.60 ± 0.03	0.62 ± 0.03		0.53 ± 0.03^***	0.556	0.101
Change		0.00 ± 0.02			− 0.09 ± 0.02				< 0.001	< 0.001
DEXA evaluation
Fat percentage (%)	31.5 ± 0.94		31.0 ± 0.94^**	29.8 ± 1.03		28.5 ± 0.98^***	0.209	0.067
Change		− 0.50 ± 0.18			− 1.26 ± 0.24				0.014	0.006
Fat mass (g)	22,826.7 ± 616.6		22,536.71 ± 606.1^*	22,038.8 ± 685.1		20,768.91 ± 651.1^***	0.395	0.050
Change		− 290.0 ± 128.4			− 1269.9 ± 221.4				< 0.001	< 0.001
Lean body mass (g)	48,289.8 ± 1471.4		48,934.6 ± 1497.4^***	50,875.5 ± 1598.1		49,726.2 ± 1567.7^***	0.237	0.716
Change		644.8 ± 168.6			− 1149.3 ± 164.3				< 0.001	< 0.001

Mean ± SE. ^∮tested following logarithmic transformation. P^a-values derived from an independent t-test between the groups at baseline. P^b-values derived from an independent t-test between the groups at follow-up. P^c-values derived from an independent t-test between the groups at changed values. P^d-values are P^c-values adjusted with the baseline values. ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001 derived from a paired t-test

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