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Table 3 Blood fatty acids profile at baseline and at the end of the study in both groups

From: The effects of EPA and DHA enriched fish oil on nutritional and immunological markers of treatment naïve breast cancer patients: a randomized double-blind controlled trial

 

Fish oil group (n = 18)

P a

Placebo group (n = 19)

P a

P b

Initial

Final

Initial

Final

Median

IQR

Median

IQR

Median

IQR

Median

IQR

Fatty acids

Saturated

58.7

50.4–63.5

58.4

50.6–64.4

0.863

52.2

49.1–60.7

55.2

48.9–59.1

0.601

0.857

Monounsaturated

10.1

9.0–11.3

9.8

8.5–10.9

0.130

9.8

9.2–12.2

10.6

8.5–11.9

0.809

0.326

Polyunsaturated

27.4

21.9–33.3

27.9

25.0–38.0

0.113

36.1

25.4–37.7

35.2

28.2–38.8

0.376

0.795

 16:0

29.9

24.6–35.1

30.4

23.6–34.7

0.356

25.0

22.1–31.3

25.7

22.7–29.6

0.717

0.824

 18:0

16.8

15.3–17.4

17.4

15.7–18.6

0.356

15.3

13.7–18.5

15.9

12.9–17.1

0.841

0.409

 18:1n-9

4.3

3.5–5.2

4.4

3.7–5.8

0.943

5.2

4.5–6.5

5.1

4.4–6.5

0.629

0.525

 20:4n-6

8.8

7.3–10.9

8.2

6.0–10.2

0.124

10.0

7.9–14.0

11.1

8.5–12.6

0.984

0.284

 20:5n-3 (EPA)

0.4

0.1–0.8

1.5

0.9–2.1

0.004

0.3

0.0–0.8

0.5

0.0–1.2

0.293

0.034

 22:6n-3 (DHA)

2.5

1.9–3.6

4.6

3.4–6.2

0.007

3.1

2.1–5.0

3.8

2.0–4.9

0.904

0.000

 Total n-3

3.3

2.4–4.9

6.5

4.3–8.7

0.004

3.7

2.6–5.9

4.1

2.9–5.9

0.952

0.005

 Total n-6

25.0

19.1–30.2

23.0

19.1–29.5

0.554

31.6

22.6–32.4

30.0

24.1–33.9

0.702

0.246

 n-6:n-3 ratio

7.7

5.3–9.7

3.8

3.0–4.7

0.002

7.0

4.5–11.1

6.8

4.4–8.8

0.904

0.012

  1. IQR Interquartile range, EPA Eicosapentaenoic acid, DHA Docosahexaenoic acid
  2. aIntragroup differences according to Wilcoxon test
  3. bInteraction test of a two-way repeated measures ANOVA for ordinal data to verify the significance of differences between fish oil and mineral oil groups