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Table 2 Nutritional status and dietary intake at baseline and at the end of the study

From: The effects of EPA and DHA enriched fish oil on nutritional and immunological markers of treatment naïve breast cancer patients: a randomized double-blind controlled trial

 

Fish oil group (n = 18)

P a

Placebo group (n = 19)

P a

P b

Initial

Final

Initial

Final

Median

IQR

Median

IQR

Median

IQR

Median

IQR

Nutritional status

 Weight (kg)

67.3

62.0–74.1

67.5

62.8–77.6

0.078

66.6

57.7–73.2

67.5

57.5–71.7

0.776

0.079

 BMI (kg/m2)

27.0

23.7–32.0

27.1

23.6–32.5

0.078

26.6

24.9–30.2

26.3

24.8–29.6

0.723

0.101

 Lean body mass (kg)

41.5

39.6–45.7

41.0

45.0–43.2

0.170

40.5

34.8–44.0

40.4

34.8–43.8

0.660

0.406

 Fat mass (kg)

26.3

19.5–33.0

26.8

21.9–34.6

0.029

26.5

21.6–30.2

24.3

22.1–29.8

0.977

0.101

 % Body fat

37.7

28.1–44.9

38.1

33.2–46.0

0.149

38.9

37.0–43.8

39.4

35.9–42.0

0.820

0.298

 SPA

−0.6

−1.2 - -0.2

−0.7

−1.1 - 0.1

0.513

−1.2

−1.6 - -0.6

−1.1

−1.63 - -0.7

0.394

0.492

Dietary intake

 Energy (kcal)

1451

1052–1755

1226

1011–1629

0.124

1162

991–1500

1289

1186–1480

0.520

0.038

 Kcal/kg

21

16–27

17

14–24

0.173

20

14–22

20

16–23

0.877

0.259

 Carbohydrates (g)

172

128–260

155

118–235

0.148

147

133–186

171

118–226

0.557

0.200

 Protein (g)

64

48–80

47

42–60

0.124

51

44–68

62

47–81

0.184

0.010

 Lipids (g)

45

34–66

42

37–51

0.124

42

33–53

38

27–53

0.546

0.686

Fat acids (g)

Saturated

11.1

7.6–15.7

9.4

8.1–13.5

0.163

8.9

7.5–13.4

9.5

6.7–13.5

0.936

0.536

Monounsaturated

11.6

9.1–19.3

10.9

7.5–13.7

0.039

10.5

8.6–14.7

9.4

6.9–15.0

0.673

0.747

Polyunsaturated

9.4

7.4–11.5

8.1

7.2–10.6

0.163

9.0

7.1–10.6

8.0

6.5–10.0

0.376

0.752

16:0

6.3

4.6–9.7

5.3

3.9–7.0

0.013

5.3

4.5–7.6

5.2

3.9–7.5

0.809

0.449

18;0

2.6

1.9–4.6

2.4

1.5–3.4

0.019

2.1

1.8–3.3

2.2

1.6–3.8

1.000

0.489

18:1n-9

10.7

8.4–17.8

10.1

7.0–12.7

0.049

9.5

7.7–13.6

8.5

6.3–14.6

0.629

0.838

18:2 n-6

7.8

6.9–9.9

7.0

6.3–9.7

0.177

7.9

6.1–9.3

7.0

5.6–8.5

0.243

0.842

18:3 n-3

0.9

0.7–1.1

0.8

0.7–1.1

0.981

0.8

0.6–0.8

0.8

0.5–0.9

0.794

0.776

20:4n-6

0.10

0.47–0.17

0.07

0.54–0.11

0.163

0.09

0.05–0.12

0.09

0.06–0.19

0.162

0.165

20:5n-3 (EPA)

0.005

0.000–0.007

0.005

0.000–0.010

0.633

0.005

0.000–0.010

0.005

0.000–0.015

0.395

0.334

22:6n-3 (DHA)

0.020

0.002–0.052

0.020

0.005–0.032

0.162

0.025

0.010–0.030

0.015

0.000–0.065

0.139

0.295

Total n-3

1.0

0.7–1.3

0.8

0.8–11

0.850

0.8

0.6–1.1

0.8

0.6–1.0

0.831

0.711

Total n-6

8.3

7.1–10.2

7.2

6.4–9.7

0.201

8.0

6.2–9.4

7.0

5.2–8.4

0.163

0.850

n-6/n-3 ratio

8.3

5.8–9.7

7.8

7.4–8.8

0.723

8.3

7.3–10.1

7.2

6.7–10.5

0.381

0.175

18:0/18:1 ratio

0.2

0.2–0.2

0.2

0.2–0.2

0.554

0.2

0.2–0.2

0.2

0.2–0.2

0.469

0.387

  1. IQR Interquartile range, BMI Body mass index, SPA Standardized phase angle, EPA Eicosapentaenoic acid, DHA Docosahexaenoic acid
  2. a Intragroup differences according to Wilcoxon test
  3. bInteraction test of a two-way repeated measures ANOVA for ordinal data to verify the significance of differences between fish oil and mineral oil groups