Apple extract treatment | Placebo treatment | ||||
---|---|---|---|---|---|
Variable | Screening (SD) | Change | Mean (SD) | Change | Mean (SD) |
Haemoglobin (g/l) | 143.1 (11.5) | 1.5 | 144.7 (1.5) | 1.4 | 144.5 (1.4) |
Haematocrit | 0.425 (0.030) | 0.001 | 0.426 (0.029) | 0.003 | 0.427 (0.030) |
Retikulocytes (E9/l) | 1.24 (0.34) | 0.06 | 1.31 (0.45) | 0.02 | 1.26 (0.42) |
Mean corpuscular volyme (fl) | 88.8 (4.3) | 0.1 | 88.9 (4.3) | 0.2 | 89.0 (4.4) |
Mean corpuscular haemoglobin (pg) | 30.0 (1.8) | 0.3 | 30.4 (2.0) | 0.1 | 30.1 (1.9) |
Leucocytes (E9/l) | 4.92 (1.27) | −0.24 | 4.64 (1.13) | −0.11 | 4.77 (1.06) |
Plasma albumin (g/l) | 39.7 (2.5) | −0.8 | 38.9 (2.0) | −1.0 | 38.8 (2.1) |
Plasma bilirubin (μmol/l) | 11.6 (6.4) | −0.4 | 11.4 (6.8) | −0.8 | 11.1 (6.0) |
Plasma alanine aminotransferase (U/l) | 25.0 (14.8) | 1.5 | 25.7 (13.9) | 2.3 | 27.1 (14.4) |
Plasma aspartate aminotransferase (U/l) | 26.6 (8.4) | −1.5 | 24.8 (6.4) | −0.1 | 26.6 (10.4) |
Plasma creatinine (μmol/l) | 78.8 (12.7) | 0.9 | 79.7 (12.6) | 0.1 | 79.1 (12.5) |
Plasma glutamyl transferase (U/l) | 27.6 (31.3) | 2.6 | 27.2 (33.9) | 5.2 | 32.7 (60.9) |
Plasma sodium (mmol/l) | 141.3 (1.6) | −0.2 | 141.1 (1.7) | −0.3 | 141.0 (1.6) |
Plasma potassium (mmol/l) | 4.00 (0.31) | 0.07 | 4.07 (0.26) | 0.05 | 4.04 (0.27) |
Fasting plasma calcium (mmol/l) | 2.31 (0.08) | 0.00 | 2.31 (0.08) | 0.00 | 2.30 (0.08) |
Fasting plasma urea (mmol/l) | 5.18 (1.18) | −0.13 | 5.03 (1.04) | 0.06 | 5.24 (1.21) |
Plasma uric acid (μmol/l) | 301.2 (72.4) | −1.5 | 298.1 (71.3) | −9.1 | 291.3 (69.3) |
Fasting plasma total cholesterol (mmol/l) | 5.65 (0.91) | −0.06 | 5.55 (1.02) | −0.09 | 5.56 (0.91) |
Fasting plasma HDL-cholesterol (mmol/l) | 1.88 (0.52) | −0.10 | 1.76 (0.49) | −0.09 | 1.78 (0.48) |
Fasting plasma LDL-cholesterol (mmol/l) | 3.27 (0.91) | 0.01 | 3.26 (0.91) | 0.02 | 3.29 (0.78) |
Fasting plasma triglycerides (mmol/l) | 1.10 (0.56) | 0.04 | 1.14 (0.72) | −0.03 | 1.07 (0.52) |
Fasting plasma glucose (mmol/l) | 5.42 (0.46) | 0.11 | 5.52 (0.48) | 0.11 | 5.52 (0.49) |
Plasma C-reactive protein (mg/l) | 2.43 (1.57) | −0.53 | 1.86 (1.23) | 1.71 | 3.75 (5.24) |