Table 3 Acute change from baseline in blood pressure and biomarkers
Apple extract treatment | Placebo treatment | |||||
|---|---|---|---|---|---|---|
Variable | Change | Mean (SD), pre | Mean (SD), post | Change | Mean (SD), pre | Mean (SD), post |
Systolic blood pressure, mm Hga | −0.6 | 145.4 (13.2) | 145.3 (15.5) | −1.6 | 148.2 (15.1) | 146.7 (14.5) |
Diastolic blood pressure, mm Hga | −0.6 | 90.3 (7.1) | 89.7 (8.0) | 0.3 | 90.3 (7.0) | 90.8 (7.1) |
s-ICAM-1, pg/mlb | −8658 | 267,737 (52847) | 259,086 (50958) | −5339 | 264,810 (58029) | 259,375 (54260) |
sVCAM-1, pg/mlb | −0.10 (log) | 1,555,001 (520492) | 1,415,276 (561821) | −0.07 (log) | 1,494,420 (500826) | 1,384,356 (422927) |
PAI-1, pg/mlb | 0.07 (log) | 55,433 (28812) | 61,956 (39638) | 0.09 (log) | 53,976 (27527) | 58,703 (29755) |
C-reactive protein, pg/mlb | −0.10 (log) | 2,791,200 (9722821) | 1,230,700 (1189128) | 0.02 (log) | 1,396,497 (2464468) | 1,530,123 (2079646) |
ADMA, μmol/lb | 0.005 | 0.776 (0.175) | 0.790 (0.144) | −0.012 | 0.791 (0.155) | 0.780 (0.154) |
vWf, ng/mlb | 0.009 (log) | 64,201 (40893) | 71,662 (71789) | 0.013 (log) | 58,823 (40455) | 65,056 (55217) |
sE-selectin, pg/mlb | 0.09 (log) | 689.2 (315.4) | 751.8 (295.6) | 0.13 (log) | 649.9 (279.8) | 741.3 (301.3) |