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Table 3 AUC measurements of gastrointestinal symptoms following consumption of low FODMAP ONS beverages and positive control

From: Gastrointestinal tolerance of low FODMAP oral nutrition supplements in healthy human subjects: a randomized controlled trial

  Positive Control Low FODMAP A Low FODMAP B Low FODMAP C  
Symptom Mean Mean Mean Mean SE P value
Baseline- 4 h post consumption
 Gas/bloating 0.25 −0.08 0.61 −0.21 0.37 0.40
 Nausea 0.24 −0.06 0.08 −0.23 0.23 0.79
 Flatulence 0.24 −0.20 0.13 0.27 0.33 0.77
 Diarrhea/loose stools 0.00 −0.18 0.02 0.00 0.09 0.36
 Constipation 0.24 −0.18 0.02 0.05 0.09 0.29
 GI rumbling 0.21 −0.12 −0.15 0.04 0.45 0.93
 GI cramping −0.08 0.07 −0.07 −0.08 0.14 0.82
 Composite GI symptom score 0.61 −0.71 0.61 −0.17 0.82 0.61
Baseline- 48 h post consumption
 Gas/bloating −2.42 −5.89 4.03 −5.83 3.73 0.21
 Nausea −6.07 −4.25 −0.77 −4.42 3.94 0.81
 Flatulence −1.02 −4.49 2.99 1.23 4.04 0.59
 Diarrhea/loose stools 2.67 −1.13 0.50 0.95 1.79 0.52
 Constipation 0.02 −1.42 1.36 0.05 1.32 0.54
 GI rumbling −4.26 −9.64 −11.20 −5.77 5.81 0.82
 GI cramping −2.18 0.07 −1.69 −1.32 2.02 0.88
 Composite GI symptom score −10.92 −26.24 −4.82 −13.40 9.91 0.48