The effect of weight loss on HDL subfractions and LCAT activity in two genotypes of APOA-II -265T>C polymorphism

Nutrition Journal

Table 3 Comparison of mean differences of variables between TT/TC and CC genotypes in APOA-II -265 T > C polymorphism

Variable	TT/TC(n = 22)	CC(n = 22)	95% confidence interval	^a P _value	^b P _value
Variable	Mean differences(SD)	Mean differences(SD)	95% confidence interval	^a P _value	^b P _value
HDL(ng/ml)	−2.81(3.94)	−1.46(3.14)	−3.5 to 0.82	0.21	0.27
HDL2(ng/ml)	0.86(0.22)	0.99(0.22)	0.75 to 1.008	0.03*	0.05*
HDL3(ng/ml)	1.004(0.14)	0.91(0.17)	0.99 to 1.19	0.06	0.02*
LCAT activity (470/390)	0.24(0.07)	0.25(0.1)	−0.06 to 0.04	0.63	0.52

HDL, High density lipoprotein; LCAT, lecithin: cholesterol acyltransferase
^amean differences of variables between two genotype without adjusting for confounders and ^bafter adjusting for differences of BMI and physical activity
*P _value was obtained from the student’s independent t-test and P _value ≤0/05 was considered as statistically significant
For HDL2 and HDL3 Geometric Mean Ratio was used

ISSN: 1475-2891